Diagnostic Accuracy of MRCP for Detecting Choledocholithaiasis in Patients with Obstructive Jaundice keep ERCP as Gold Assistant
DOI:
https://doi.org/10.51985/Keywords:
MRCP, ERCP, choledocholithiasis, obstructive jaundice, diagnostic accuracyAbstract
Objective: To determine the diagnostic accuracy of MRCP for detecting choledocholithiasis in patients with obstructive jaundice keeping ERCP as gold standard.
Study Design and settings: Cross-sectional validation study, Department of Radiology, Madinah Teaching, Faisalabad.
Methods: Non-probability consecutive sampling was used to sample 230 patients of both genders, aged 26-70 years, and
experiencing obstructive jaundice. Patients who had been diagnosed with choledocholithiasis earlier, with chronic liver
disease or have a contraindication to MRI were not included. MRCP was performed on all enrolled patients that underwent
ERCP in 48 hours. Findings on MRCP were compared to ERCP findings. The SPSS version 20 was used to analyze data.
A 2 x 2 contingency table was used to calculate sensitivity, specificity, positive predictive value, negative predictive value
and diagnostic accuracy.
Findings: The average age of the patients was 48.72 + 11.43 years. Out of 230 patients, 132 (57.4%) were male and 98
(42.6%) were female. In 168 (73.0) patients, MRCP observed choledocholithiasis whereas in 174 (75.7) patients, ERCP agreement was choledocholithiasis. The diagnostic accuracy, sensitivity, specificity, positive predictive value, negative predictive value for MRCP were 91.95%, 85.71%, 95.24%, 77.42%, 90.43% respectively.
Conclusions: MRCP was found very accurate in diagnosing choledocholithiasis among patients presenting with obstructive jaundice.
Keywords: MRCP, ERCP, choledocholithiasis, obstructive jaundice, diagnostic accuracy
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