Comparative Study between the Effects of Dexmedetomidine and Lidocaine Infusion on Intraoperative Hemodynamic and Requirement of Nalbuphine for Postoperative Analgesia in Upper Limb Orthopaedic Surgeries
DOI:
https://doi.org/10.51985/JBUMDC2025758Keywords:
Dexmedetomidine, Heart rate, Lidocaine, Mean Arterial Pressure, Numeric rating scaleAbstract
Objectives: To compare the intraoperative and postoperative hemodynamics and requirement of nalbuphine for postoperative
analgesia in upper limb orthopedic surgeries between dexmedetomidine and lidocaine.
Study Design: Comparative analytical study
Place and duration of study: Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi, Pakistan from 17th Oct
22 to 15th July 23.
Methodology: Patients undergoing upper limb orthopedic surgeries in our tertiary care setup. Ninety patients undergoing
upper limb orthopaedic surgeries were divided into two equal groups of forty-five patients each. Group A received
Dexmedetomidine infusion, while Group B received Lidocaine infusion. Data collection involved gathering information
related to upper limb orthopaedic procedures, including both intraoperative and postoperative parameters.
Results: Ninety patients undergoing upper limb surgeries were randomized into two groups (Dexmedetomidine: Group
A, Lidocaine: Group B). Group A experienced statistically significant reductions in intraoperative mean arterial pressure
(MAP) by 20% (p<0.05) and heart rate (HR) by 15% (p<0.01) compared to Group B at all time points (10-120 minutes).
Postoperative pain scores were significantly higher in Group B (mean difference: 1.5 points, p<0.001) across all time points
(2-24 hours). Group A also exhibited significantly higher sedation scores (mean difference: 2 points, p<0.001) and required
significantly less postoperative analgesia (one dose vs. multiple doses, p<0.001) than Group B.
Conclusion: The findings affirm dexmedetomidine infusion's advantages in achieving optimal outcomes: improved
hemodynamics, reduced pain, and lowered postoperative analgesic demands, reinforcing its role in effective pain management.
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