Accuracy of Knee MRI Findings in Detecting Soft Tissue Injury, Taking Arthroscopy as the Gold Standard

Authors

  • Zeeshan Haider Author
  • Abbas Ali Author
  • Shehryar Khan Author
  • Luqman Khan Author
  • Ubaid Ullah Author
  • Waqas Ahmad Author

DOI:

https://doi.org/10.51985/JBUMDC2025777

Keywords:

Anterior Cruciate Ligament Injuries, Arthroscopy, Diagnostic Imaging, Knee Injuries,

Abstract

 Objective: To assess the diagnostic validity of Magnetic Resonance Imaging (MRI) in detecting soft tissue knee injuries
using arthroscopy as the gold standard.
Study Design and Setting: A cross-sectional validation study was conducted at Khyber Teaching Hospital, Peshawar.
Methodology: A total of 192 patients with clinical suspicion of soft tissue knee injury were enrolled using non-probability
consecutive sampling for six months from 1st January 2025 to 30th June 2025. Inclusion criteria involved patients aged
18–60 years presenting with knee pain (VAS >4) and a popping sound, with normal X-ray findings. MRI scans were
interpreted for the presence of soft tissue tears based on hyperintense signals on T2-weighted images and fiber discontinuity.
All patients subsequently underwent arthroscopic evaluation. The diagnostic accuracy of MRI was determined using
sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Cohen’s Kappa for agreement.
Results: MRI showed high sensitivity for the medial meniscus (91.8%), anterior cruciate ligament (88.6%), and posterior
cruciate ligament (83.3%), while the lateral meniscus had moderate sensitivity (68.2%). Specificity ranged from 74.3%
(medial meniscus) to 86.7% (lateral meniscus). Agreement between MRI and arthroscopy was substantial for medial
meniscus injuries (ê = 0.81) and moderate for anterior cruciate ligament, posterior cruciate ligament, and lateral meniscus.
Conclusion: MRI has high diagnostic utility and a substantial agreement with arthroscopy, specifically for anterior cruciate
ligament and medial meniscus injuries. Given its non-invasive nature and strong predictive validity, MRI should be
considered an effective first-line diagnostic tool when evaluating soft tissue knee injuries. 

References

1. Maniar N, Verhagen E, Bryant AL, Opar DA. Trends in

Australian knee injury rates: An epidemiological analysis of

228,344 knee injuries over 20 years. Lancet Reg Health West

Pac. 2022 Mar 22;21:100409. doi: 10.1016/j.lanwpc. 2022.

100409.

2. Khan AA, Ahmad A, Yunus MF, Samad A. Knee problems

and possible support for rehabilitation review. Int J Forensic

Eng Manag. 2023;1(3):242–262. doi: 10.1504/IJFEM.2023.

136349

3. Pramanik K. Stem Cell and Tissue Engineering: Bone,

Cartilage, and Associated Joint Tissue Defects. 1st ed. Boca

Raton: CRC Press; 2024 [cited 2025 Aug 5]. Available from:

https://doi.org/10.1201/9781003245353

4. Fritz B, Fritz J. Artificial intelligence for MRI diagnosis of

joints: a scoping review of the current state-of-the-art of deep

learning-based approaches. Skeletal Radiol. 2022

Feb;51(2):315–329. doi: 10.1007/s00256-021-03830-8.

5. Li G, Niu W. Challenges toward musculoskeletal injuries and

diseases. In: Nanoengineering in Musculoskeletal

Regeneration. Academic Press; 2020. p. 1–41. doi: 10.1016

/B978-0-12-820262-3.00001-3

6. Albano D, Viglino U, Esposito F, Rizzo A, Messina C, Gitto

S, et al. Quantitative and Compositional MRI of the Articular

Cartilage: A Narrative Review. Tomography. 2024 Jun

24;10(7):949–969. doi: 10.3390/tomography10070072.

7. Nacey NC, Geeslin MG, Miller GW, Pierce JL. Magnetic

resonance imaging of the knee: An overview and update of

conventional and state-of-the-art imaging. J Magn Reson

Imaging. 2017 May;45(5):1257–1275. doi: 10.1002/

jmri.25620.

8. Chen F, Cui X, Han B, Liu J, Zhang X, Liao H. Augmented

reality navigation for minimally invasive knee surgery using

enhanced arthroscopy. Comput Methods Programs Biomed.

2021 Apr;201:105952. doi: 10.1016/j.cmpb.2021.105952.

9. Rathod V, Shrivastav S, Gharpinde MR. Knee Arthroscopy

in the Era of Precision Medicine: A Comprehensive Review

of Tailored Approaches and Emerging Technologies. Cureus.

2024 Oct 6;16(10):e70932. doi: 10.7759/cureus.70932.

10. Dawkins BJ, Kolin DA, Park J, Fabricant PD, Gilmore A,

Seeley M, et al. Sensitivity and Specificity of MRI in

Diagnosing Concomitant Meniscal Injuries With Pediatric

and Adolescent Acute ACL Tears. Orthop J Sports Med. 2022

Mar 9;10(3):23259671221079338. doi: 10.1177/ 232596

71221079338.

11. Wang W, Li Z, Peng HM, Bian YY, Li Y, Qian WW, et al.

Accuracy of MRI Diagnosis of Meniscal Tears of the Knee:

A Meta-Analysis and Systematic Review. J Knee Surg. 2021

Jan;34(2):121–129. doi: 10.1055/s-0039-1694056.

12. Spinnato P, Patel DB, Di Carlo M, Bartoloni A, Cevolani L,

Matcuk GR, et al. Imaging of Musculoskeletal Soft-Tissue

Infections in Clinical Practice: A Comprehensive Updated

Review. Microorganisms. 2022 Nov 25;10(12):2329. doi:

10.3390/microorganisms10122329.

13. Bin Abd Razak HR, Sayampanathan AA, Koh TH, Tan HC.

Diagnosis of ligamentous and meniscal pathologies in patients

with anterior cruciate ligament injury: comparison of magnetic

resonance imaging and arthroscopic findings. Ann Transl

Med. 2015 Oct;3(17):243. doi: 10.3978/j.issn.2305-5839.

2015.10.05.

14. Li M, Khan L, Imran S, et al. Towards Precision Medicine:

Tailoring Diagnosis Based on MRI Evaluation of Adult Lateral

Discoid Meniscus Injury. Preprint. 2024 Jun 27; Version 1.

Available from: https://doi.org/10.21203/rs.3.rs-4551558/v1

15. Li X, Hou Q, Zhan X, Chang L, Ma X, Yuan H. The accuracy

of MRI in diagnosing and classifying acute traumatic multiple

ligament knee injuries. BMC Musculoskelet Disord. 2022

Jan 13;23(1):43. doi: 10.1186/s12891-021-04976-1.

16. Vo TT, Nguyen DT, Dinh Le NA, Van Nguyen KH, Vuu HK,

Le TA, Le Phan NB. Evaluation of meniscal injury on magnetic

resonance imaging and knee arthroscopy in patient with

anterior cruciate ligament tear. SICOT J. 2024;10:56. doi:

10.1051/sicotj/2024051

17. Koch JEJ, Ben-Elyahu R, Khateeb B, Ringart M, Nyska M,

Ohana N, et al. Accuracy measures of 1.5-tesla MRI for the

diagnosis of ACL, meniscus and articular knee cartilage damage

and characteristics of false negative lesions: a level III prognostic

study. BMC Musculoskelet Disord. 2021 Jan 29;22(1):124. doi:

10.1186/s12891-021-04011-3.

18. Botnari A, Kadar M, Patrascu JM. A Comprehensive Evaluation

of Deep Learning Models on Knee MRIs for the Diagnosis and

Classification of Meniscal Tears: A Systematic Review and

Meta-Analysis. Diagnostics (Basel). 2024 May 24;14(11):1090.

doi: 10.3390/diagnostics14111090.

19. Shantanu K, Singh S, Srivastava S, Saroj AK. The Validation of

Clinical Examination and MRI as a Diagnostic Tool for Cruciate

Ligaments and Meniscus Injuries of the Knee Against Diagnostic

Arthroscopy. Cureus. 2021 Jun 17;13(6):e15727. doi: 10.7759/

cureus.15727.

20. Nakagawa Y, Mukai S, Sakai S, Nakamura R, Takahashi M,

Nakagawa S. Preoperative diagnosis of knee cartilage, meniscal,

and ligament injuries by magnetic resonance imaging. J Exp

Orthop. 2023 Apr 20;10(1):47. doi: 10.1186/s40634-023-00595-

y.

21. Dhall A, Agrawal S, Thukral B, Swarup A. MRI evaluation

of knee trauma and its correlation with clinical examination

and arthroscopic findings. Int J Radiol Diagn Imaging.

2021;4:84–87. doi: 10.33545/26644436.2021.v4.i1b.166

22. Abdullahi M, Museve G, Odero N, Munene O, Panwar P,

Adan S. A comparison of MRI and arthroscopic findings of

intra-articular soft tissue injury of the knee at Kenyatta National

Hospital, Kenya. East Afr Orthop J. 2024;18(2):97–101. doi:

10.4314/eaoj.v18i2.7

23. Li X, Li D, Li J, Wang G, Yan L, Liu H, et al. Preclinical

Studies and Clinical Trials on Cell-Based Treatments for

Meniscus Regeneration. Tissue Eng Part B Rev. 2023

Dec;29(6):634–670. doi: 10.1089/ten.TEB.2023.0050.

24. Behr J, Nich C, D'Assignies G, Zavastin C, Zille P, Herpe G,

et al. Deep learning-assisted detection of meniscus and anterior

cruciate ligament combined tears in adult knee magnetic

resonance imaging: a crossover study with arthroscopy

correlation. Int Orthop. 2025 Jul;49(7):1689–1697. doi:

10.1007/s00264-025-06531-2.

25. Pawal S, Badhe PV, Arkar R, Varrior A, Nagure P, Patil S, et

al. Role of MRI in knee joint injuries in correlation with

arthroscopy. Int J Acad Med Pharm. 2023;5(3):2125–2130.

doi: 10.47009/jamp.2023.5.3.418

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Published

2026-01-14

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