Relationship between Preoperative Risk Factors and Need for Blood Transfusion in Transurethral Resection Of The Prostate (TURP)

Authors

  • Mukaram Ashraf Author
  • Jai Kumar Author
  • Lajpat Rai Author
  • Anila Jamshaid Author
  • Viran Raj Kamal Author
  • Muhammad Haroon Author

DOI:

https://doi.org/10.51985/

Keywords:

Aged; Blood Transfusion; Hemoglobin; Prostatic Hyperplasia; Transurethral Resection of Prostat

Abstract

 Objective: To assess the incidence of blood transfusion after transurethral resection of the prostate (TURP) and to examine the relationship between preoperative risk factors and need for blood transfusion.

 

Study design and Setting: Descriptive study conducted in the Department of Urology, The Indus Hospital and health network, Karachi from 1st Sep’ 2024 to 28th Feb’ 2025.

 

Methodology: Sixty patients who underwent TURP after approval by the IRB. Patients with bleeding diatheses, anticoagulant use within the previous 2 weeks prior to surgery or preoperative treatment with 5-alpha reductase inhibitors were excluded. The data was written on predesigned proforma and analyzed by using SPSS V.26. Risk factors were evaluated in patients who needed transfusion. Univariate analysis was performed by descriptive statistics and Chi-square or Fischer’s exact test as appropriate, the level of significance adopted being p<0.05.

 

Results: Sixty patients were enrolled with a mean age of 67 ± 7.29 years. Hemoglobin and hematocrit decreased from 13.1 ± 1.42 g/dl and 39.7 ± 4.27% preoperatively to 12.3 ± 1.61 g/dl and 37.1 ± 4.68% postoperatively, with median reductions of 0.7 g/dl and 2.35%, respectively. Hypertension (28.2%) and diabetes (15.4%) were the most common comorbidities; 39.7% had none. Only one patient (1.7%) required transfusion, associated with indwelling catheter, prior TURP, short symptom duration, and prostate size of 40–60 g. No significant association between risk factors and transfusion was observed.

 

Conclusions: The rate of transfusion after TURP was low, Universal cross-matching and prearrangement of blood in all patients are probably not indicated 

References

1. Kim J, Alrumaih A, Donnelly C, Uy M, Hoogenes J,

Matsumoto ED. The impact of tranexamic acid on perioperative

outcomes in urological surgeries: a systematic review and

meta-analysis. Can Urol Assoc J. 2023 Jun; 17(6):205-16.

DOI: https://doi.org/10.5489/cuaj.8254

2. Vanderbruggen W, Van Poppel H, Oudenhoven L, et al. The

effect of tranexamic acid on perioperative blood loss in

transurethral resection of the prostate: a double-blind,

randomized controlled trial. Prostate. 2023 Aug 21. DOI:

https://doi.org/10.1002/pros.246163. Pastene B, Bernard R, Colin M, et al. Patient Blood

Management in transurethral resection surgery: overview and

strategy analysis from a French tertiary hospital. Adv Ther.

2023 Apr; 40(4):1830-37.

4. Porto JG, Bhatia AM, Bhat A, et al. Evaluating transurethral

resection of the prostate over twenty years: a systematic

review and meta-analysis of randomized clinical trials. World

J Urol. 2024 Nov; 42(1):639. DOI: https://doi.org/10.1007/

s00345-024-05332-3

5. Kuo LY, Kuo J, Silverman J, et al. Comparison of perioperative

bleeding risk between direct oral anticoagulants in transurethral

resection of prostate. BJU Int. 2024 Aug; 134(1):30-37. DOI:

https://doi.org/10.1111/bju.16478

6. Eraky AM, Rubenstein SC, Khan A, Mokhtar Y, Gregorich

NM. Non-surgical bleeding and transurethral resection of the

prostate (TURP) syndrome after TURP surgery: a case report

and literature review. Pathophysiology. 2024 Jul; 31(3):367-

75. DOI: https://doi.org/10.3390/pathophysiology31030027

7. Lotterstätter M, Seklehner S, Wimpissinger F, et al.

Transurethral resection of the prostate in 85+ patients: a

retrospective, multicentre study. World J Urol. 2022; 40(2):

DOI: https://doi.org/10.1007/s00345-022-04179-w

8. Adhikari B, Shrestha A, Basnet RB, Shrestha PM, Gharti BB,

Shah AK. Monopolar transurethral resection of prostate for

benign prostatic hyperplasia in patients with and without

preoperative urinary catheterisation: a prospective comparative

study. Cureus. 2021 Jul 28; 13(7):e16705. DOI: https://doi.org/

10.7759/cureus.16705

9. Hughes T, Harper P, Somani BK. Treatment algorithm for

management of benign prostatic obstruction: an overview of

current techniques. Life. 2023 Oct 18; 13(10):2077. DOI:

https://doi.org/10.3390/life13102077

10. Miernik A, Gratzke C. Current treatment for benign prostatic

hyperplasia. Dtsch Arztebl Int. 2020 Dec; 117(49):843-54.

DOI: https://doi.org/10.3238/arztebl.2020.0843

11. Young MJ, Elmussareh M, Morrison T, Wilson JR. The

changing practice of transurethral resection of the prostate.

Ann R Coll Surg Engl. 2018 Mar; 100(4):326-9. DOI:

https://doi.org/10.1308/rcsann.2018.0054

12. Issa MM. Technological advances in transurethral resection

of the prostate: bipolar versus monopolar TURP. J Endourol.

2008 Aug; 22(8):1587-96. DOI: 10.1089/end.2008.0192

13. Shrestha BM, Prasopshanti K, Matanhelia SS, Peeling WB.

Blood loss during and after transurethral resection of prostate:

a prospective study. Kathmandu Univ Med J (KUMJ). 2008

Jul-Sep;6(23):329-34. DOI: https://doi.org/10.3126/ kumj.v6i3.

1707

14. Smith H, Falconer R, Szczachor J, Ahmad S. Routine

preoperative group and save for TURP and TURBT – need

and cost-effectiveness. J Clin Urol. 2018 Jan;11(1):33-7. DOI:

https://doi.org/10.1177/2051415817717908

15. Olapade-Olaopa EO, Solomon LZ, Carter CJ, Ahiaku EK,

Chiverton SG. Haematuria and clot retention after transurethral

resection of the prostate: a pilot study. Br J Urol. 1998 Nov;

82(5):624-7. DOI: 10.1046/j.1464-410x.1998.00824.x

16. Levin K, Nyren O, Pompeius R. Blood loss, tissue weight

and operating time in transurethral prostatectomy. Scand J

Urol Nephrol. 1981; 15(3):197-200. DOI: 10.3109/ 00365598

109179602

17. Kirollos MM, Campbell N. Factors influencing blood loss in

transurethral resection of the prostate (TURP): auditing TURP.

Br J Urol. 1997; 80(1):111-5. DOI: 10.1046/j.1464-410x.1997

.00253.x

18. Li Z, et al. Venous thromboembolism and bleeding after

TURP: effect of preoperative antithrombotic therapy history

on bleeding and VTE. J Clin Med. 2023;12(2):417. DOI:

https://doi.org/10.3390/jcm12020417

19. Smith H, Falconer R, Szczachor J, Ahmad S. Routine

preoperative group and save for TURP and TURBT – need

and cost effectiveness. Journal of Clinical Urology.

2017;11(1):33-37. doi:10.1177/2051415817717908

20. Lee SH, Cho E, Park JH, Lee JY, Hong JH, Han H. Addressing

desaturation in a tracheal stenosis patient using the transnasal

humidified rapid-insufflation ventilatory exchange technique

during tracheostomy: A case report. Medicine (Baltimore).

2023;102(31):e34567. DOI:

21. John A, Mian M, Sreedharan S, Kahokehr AA. The impact

of the coronavirus disease 2019 pandemic on elective urological

procedures in Australia. Asian J Urol. 2022;9(1):35-41. DOI:

https://doi.org/10.1016/j.ajur.2021.07.001

22. Salehi M, Imani B, Zandi S, et al. Effect of tranexamic acid

dissolved in warm, cold, and room-temperature irrigation

fluid on complications during and after TURP surgery: A

double-blind, randomized clinical trial. Afr J Urol. 2025;31:4.

DOI: https://doi.org/10.1186/s12301-025-00476-z

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Published

2026-04-21

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How to Cite

Relationship between Preoperative Risk Factors and Need for Blood Transfusion in Transurethral Resection Of The Prostate (TURP). (2026). Journal of Bahria University Medical and Dental College, 16(02), 538-543. https://doi.org/10.51985/

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