Late Onset neurofibromatosis (NF-VII) presenting with segmental distribution of lesions: A novel case report
DOI:
https://doi.org/10.51985/Keywords:
Late onset, Neurofibromatosis, SegmentalAbstract
Neurofibromatosis (NF) is a hemartoneoplastic syndrome with up to eight possible variants. By far NF Type I is the most common presentation. A 74 years old gentleman present at our dermatology OPD with history of asymptomatic progressive nodular lesions appearing on his left arm only for past 4 years. The family history was insignificant and examination revealed soft pedunculated skin-colored nodules of varying sizes distributed primarily over flexor aspect of left arm. There were no associated pigmentary changes or lisch nodules. Excisional biopsy reveled a well-circumscribed nodular lesion in dermis composed of multiple spindle cells packed loosely in myxoid stroma with scattered mast cells.
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