Comparison of Six-Strand and Four-Strand Techniques for the Repair of Injured Zone II Flexor Tendons of the Hand: A Randomized Controlled Trial
DOI:
https://doi.org/10.51985/Keywords:
Flexor tendon repair; Hand injuries; Tendon injuriesAbstract
Objective: To compare the functional outcomes of six-strand and four-strand techniques for repair of injured flexor tendons of zone II of the hand.
Study Design and Setting: Randomized controlled trial—Department of Plastic Surgery, Allied Hospital, Faisalabad, from 27th January 2026 to 26th April 2026.
Methodology: A total of 136 patients with clean, sharp zone II flexor tendon injuries presenting within one week of trauma were randomized into two equal groups (n = 68 each). Group A received four-strand repair, and Group B received six-strand repair. All patients were managed with dorsal blocking splintage and early mobilization using the modified Kleinert protocol. Functional outcomes were assessed at three months using Tang criteria. This study analysed data using IBM SPSS version 25, with p < 0.05 considered significant.
Results: Group B had a statistically significantly higher mean overall active movement than Group A (218.46 ± 25.31 degrees vs 190.85 ± 28.72 degrees; p<0.001). The mean extension deficit was lower in Group B than in Group A (12.41 ± 6.78 degrees vs 18.94 ± 8.36 degrees; p<0.001). There was an excellent functional outcome in the six-strand group (52 (76.5)) versus the four-strand group (36 (52.9)) cases. In Group B, the final desirable outcome (excellent and good results) was observed in 94.1% of patients, compared with 79.4% in Group A (p=0.023).
Conclusion: Six-strand flexor tendon repair demonstrated superior functional outcomes compared with four-strand repair in zone II hand injuries, with a higher rate of excellent results, greater total active movement, and reduced extension deficit
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References
1. Tang JB, Lalonde D, Harhaus L, Sadek AF, Moriya K, Pan
ZJ. Flexor tendon repair: recent changes and current methods.
J Hand Surg Eur. Vol. 2022 Jan;47(1):31-39. doi: 10.1177/17
531934211053757
2. Hong DY, Strauch RJ. Flexor Tendon Zone II Repair. JBJS
Essent Surg Tech. 2023 Oct 4;13(4):e22.00057. doi:
10.2106/JBJS.ST.22.00057
3. Haas-Lützenberger EM, Strolla J, Giunta R, Volkmer E.
Aktuelle Trends in der Beugesehnenchirurgie – Ergebnisse
einer nationalen Online-Umfrage [Current Trends in Flexor
Tendon Surgery: Results of a National Online Survey].
Handchir Mikrochir Plast Chir. 2023 Sep;55(5):350-357.
German. doi: 10.1055/a-2060-0755
4. Wirtz C, Leclère FM, Oberfeld E, Unglaub F, Vögelin E. A
retrospective analysis of controlled active motion versus
modified Kleinert/Duran rehabilitation protocol in flexor
tendon repair, zones I and II, in a single centre. Arch Orthop
Trauma Surg. 2023 Feb;143(2):1133-1141. doi:
10.1007/s00402-022-04506-1
5. Peters SE, Jha B, Ross M. Rehabilitation following surgery
for flexor tendon injuries of the hand. Cochrane Database
Syst Rev. 2021 Jan 13;1(1): CD012479. doi: 10.1002/
14651858. CD012479.pub2
6. Lindsay C, Watson N, Yanik J, Glass N, Fowler T. Strength,
bulk and surgery time of ex situ versus in situ flexor tendon
repair in a cadaveric model. J Hand Surg Eur Vol. 2023
Feb;48(2):137-143. doi: 10.1177/17531934221131376
7. Kusano N, Zaegel MA, Silva MJ. Cyclic testing of six-strand
suture techniques for zone 2 flexor tendon lacerations. J
Orthop Sci. 2024 Sep;29(5):1214-1219. doi: 10.1016/j.jos.
2023.09.007
8. Abdelmalek A, McFarlane J. Is releasing pulleys during flexor
tendon repair “part and parcel”? Narrative review of the
current evidence. Eur J Orthop Surg Traumatol. 2022
Nov;32(8):1451-1457. doi: 10.1007/s00590-021-03128-4
9. Heydari MB, Porhesam Y, Karimi Rouzbahani A,
Mahmoudvand G, Mahmoudvand H. Comparison of Sixstrand and Four-strand Techniques on the Repair of Injured
Deep Flexor Tendons of Zone II of the Hand: A Randomized
Controlled Clinical Trial. World J Plast Surg. 2023;12(2):34-
40. doi: 10.52547/wjps.12.2.34
10. Douwes TA, Bulstra AEJ, Buijze GA. Flexor tendon repair
in zone II of the hand: Evidence-based management. Hand
Surg Rehabil. 2025 Sep;44(4):102230. doi: 10.1016/j.hansur.
2025.102230.
11. Naseem A, Ali FA, Hyder A, bin Waheed U, Ali M, Tasleem
S. Comparison of Outcome Between Early and Delayed Repair
of Flexor Tendons. Pakistan Armed Forces Medical Journal.
2024 Jun 30;74(3):749. doi:10.51253/pafmj.v74i3. 8056
12. Mujahid AM, Saleem M, Ahmadi S, Khalid FA, Yousaf MA,
Abidin ZU, Tarar MN. Comparison of outcome of 1-and 2-
knot, 4-strand, double-modified kessler flexor tendon repair
with early active mobilization protocol in patients with flexor
tendon lacerations of hand. Journal of Ayub Medical College
Abbottabad. 2018 Nov 26;30(4):544-7. https://jamc.ayubmed.
edu.pk/index.php/jamc/article/view/5388/2027
13. Ranjan V, Singh A, Kumar P, Sharma R, Gupta RK, Verma
R, et al. Outcomes of flexor tendon injury repair of the hand:
a prospective observational study. J Hand Microsurg.
2023;15(2):118-125. doi: 10.1055/s-0043-1761935
14. Mortada H, Alnaser A, Alhammadi T, Khan W, Alabdulla M,
Ahmed M, et al. Maximizing hand function following zone
II flexor tendon repair: current concepts and outcomes. Hand
Surg Rehabil. 2024;43(6):101782. doi: 10.1016/j.hansur.
2024.101782
15. Renberg M, Svingen J, Arner M, Farnebo S. Range of motion
following flexor tendon repair in zone II injuries. J Hand Surg
Am. 2024;49(12):1203-1210. doi: 10.1016/j.jhsa.2024.06.018
16. Emir Z, Çoban YK, Özdemir M, Demirkan F, Yýldýrým S,
Akçal MA. Delayed primary flexor tendon repair in zone II
injuries: functional outcomes and complications. Hand Surg
Rehabil. 2025;44(1):101995. doi: 10.1016/j.hansur.2024.
101995
17. Osada D, Fujita S, Tamai K, Yamaguchi T, Iwamoto A,
Saotome K. Flexor tendon repair in zone II with 6-strand
techniques and early active mobilization. J Hand Surg Am.
2006;31(6):987-992. doi: 10.1016/j.jhsa.2006.03.018
18. Tobler-Ammann BC, Leclercq C, Meyer VE, Calcagni M,
Schweizer A, Farron A, et al. Outcomes of 218 primary singlefinger flexor tendon repairs up to 1 year after surgery. J Hand
Surg Eur Vol. 2023;48(8):845-853. doi: 10.1177/17531
934231187045
19. Wimbiscus M, Smith R, Jones C, Patel A, Nguyen D, Wallace
E, et al. Advances and challenges in zone II flexor tendon
repairs. Ann Plast Surg. 2024;93(4):455-462. doi: 10.1097/
SAP.0000000000004021
20. Xu H, Wang Y, Li Z, Chen S, Liu P, Zhang C, et al. Outcome
of surgical repair and rehabilitation of flexor tendon injuries
in zone II of the hand: a systematic review and meta-analysis.
J Hand Surg Am. 2022;47(5):456.e1-456.e12. doi:
10.1016/j.jhsa.2021.11.013
21. Karacam S, Özkan FU, Yýldýz C, Çelik D, Keskinbora M,
Koca K. Flexor tendon repair rehabilitation practices in
Türkiye: a national survey study. Acta Orthop Traumatol Turc.
2023;57(4):233-239. doi: 10.5152/j.aott.2023.22183
22. Chinchalkar SJ, Gan BS, Grewal R, MacDermid JC, Faber
KJ, King GJW, et al. Zone-specific pitfalls in flexor tendon
rehabilitation. J Hand Ther. 2024;37(3):412-420. doi:
10.1016/j.jht.2023.09.008
23. El-Gammal TA, El-Sayed A, Kotb MM, Elshazly O, Moustafa
MF, Ahmed A. Outcomes of zone II flexor tendon repair
under WALANT versus general anesthesia. J Hand Surg Asian
Pac Vol. 2024;29(2):201-209. doi: 10.1142/S2424835
524500184
24. McLaughlin MT, Nydick JA, Hess AV, Stone JD, Klifto KM,
Izaddoost SA, et al. Insurance status predicts hand therapy
adherence following flexor tendon repair. Plast Reconstr Surg.
2024;153(5):942e-951e. doi: 10.1097/PRS.0000000000010935
25. Sadagatullah AN, Raghu S, Paiman M, Ismail S, Jusoh MH.
Biomechanical evaluation of flexor tendon repair techniques:
current evidence and future directions. Malays Orthop J.
2025;19(2):1-8. doi: 10.5704/MOJ.2507.001
26. Suszynski TM, Gruson KI, Fowler JR, Kamal RN, Osei DA,
Goldfarb CA, et al. Flexor tendon repair in zone II augmented
with an externalized detensioning suture. J Hand Surg Am.
2023;48(9):881.e1-881.e8. doi: 10.1016/j.jhsa.2023.02.017
27. Johnson SP, Kelley BP, Waljee JF, Chung KC. Effect of time
to hand therapy following zone II flexor tendon repair. Plast
Reconstr Surg. 2021;147(3):469e-478e. doi:
10.1097/PRS.0000000000007667
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