Effect Of Citrullus Lanatus Juice On Hemoglobin, Red Blood Cells And Liver Enzyme; An Experimental Study

Authors

  • Shahid Ali
  • Nuzhat Sultana
  • Muslim Abbas
  • Zareen Naz
  • Muhammad Akbar Hassan
  • Muhammad Abid

DOI:

https://doi.org/10.51985/JBUMDC2019023

Abstract

Objective: To determine effect of citrullus lanatus juice on hemoglobin and Serum Glutamic Pyruvic Transaminase (SGPT)
level.
Study design and setting: It was an experimental study conducted on healthy rabbits for sixty days in the research
department of pharmacy University of Karachi.
Methodology: Current study was planned to evaluate effect of Citrullus lanatus juice on red blood cells, hemoglobin and
liver enzyme. 60 days study was performed at 2 different doses i.e 3and 6ml/kg on rabbits. These rabbits were from either
gender and were divided into 3 groups their weight ranges from 1200 to 1800 grams. Group A is control group (Normal
saline 6ml/kg), Group B is treated group (3 ml/kg), Group C is treated group (6ml/kg). After taking mean of all values they
are compared with control group. Significance of mean can be estimated by Tukes Post Hoc Test. P<0.05 estimated as
significant.
Results: It was found that count of red blood cells rises significantly along with rise in hemoglobin level. As far as liver
enzyme serum glutamate pyruvate transaminase (SGPT) was concerned its concentration decreases slightly.
Conclusion: Citrullus lanatus juice contain ingredients which are important for RBC hemoglobin and synthesis .It also
contains important antioxidants that have organoprotective role due to which SGPT level decreases even in healthy animals
as compared to control groups.

References

WHO & FAO.(2003). Diet, nutrition & the prevention of chronic diseases: In report of a joint WHO/FAO Expert consultation. Geneva: WHO.

Shiundu, K, M. Role of African leafy vegetables in alleviating food and nutrition insecurity in Africa. AJFNS. 2004: 2(2);96-97.

Rhodes B, Zhang X.(2000). Hybrid seed production in watermelon. Journal of new seeds;1(3-4):69-88.

Edwards AJ, Vinyard BT, Wiley ER, Brown ED, Collins JK, Perkins-Veazie P, Baker RA, Clevidence BA. Consumption of watermelon juice increases plasma concentrations of lycopene and â-carotene in humans. The Journal of nutrition;2003:133(4)1043-50.

Wasylikowa K, Van der Veen M. An archaeobotanical contribution to the history of watermelon, Citrullus lanatus (Thunb.) Matsum. &Nakai (syn. C. vulgaris Schrad.). Vegetation History and archaeobotany;2004:13(4);213-7.

Fursa TB. Intraspecific classification of water-melon under cultivation. Genetic Resources and Crop Evolution; 1981:29(1);297-300.

Maynard, D. N(2001). Watermelons: characteristics, production and marketing. ASHS Press.

Oyolu, C. A (1977) quantitative and qualitative study of seed types in egusi (Colocynthiscitrullus L.). Tropical science.

Lucier, G., & Lin, B. H. Factors affecting watermelon consumption in the United States. Washington DC: Department of Agriculture, Economic Research Service. http://www. ers. usda. gov/Briefing/vegetables/ vegpdf/ WatermelonFactors. pdf, 2001:3(14):08.

Zohary, D., Hopf, M., & Weiss, E. (2012). Domestication of Plants in the Old World: The origin and spread of domesticated plants in Southwest Asia, Europe, and the Mediterranean Basin. Oxford University Press on Demand.

Naz, A., Butt, M. S., Pasha, I., & Nawaz, H. (2013). Antioxidant indices of watermelon juice and lycopene extract. Pakistan Journal of Nutrition, 2013:12(3);255.

Leskovar D, Bang H, Crosby K, Maness N, Franco A, Perkins-Veazie P. Lycopene, carbohydrates, ascorbic acid and yield components of diploid and triploid watermelon cultivars are affected by de® cit irrigation. The Journal of Horticultural Science and Biotechnology;2004:79(1);75-81.

Bruton BD, Fish WW, Roberts W, Popham TW. (2009). The Influence of Rootstock Selection on Fruit Quality CDmB kk. Open food science journal; doi: 10.5154/r.rchsh. 2016.06.019

USDA, (2002). USDA nutrient database for standard reference, release 15. [Internet] U.S. Department of Agriculture, Beltsville Human Nutrition Research Center, Beltsville Md, United States. http://www.nal.usda. gov/fnic /foodcomp. Accessed June 2003.

Fu WJ, Haynes TE, Kohli R, Hu J, Shi W, Spencer TE, Carroll RJ, Meininger CJ, Wu G.(2005). Dietary L-arginine supplementation reduces fat mass in Zucker diabetic fatty rats. The Journal of Nutrition. 2005:135(4);714-21.

Pinto P, Santos C, Henriques C, Lima MG, Quedas MF.(2011). Lycopene content and antioxidant capacity of Portuguese watermelon fruits. Electronic Journal of Environmental, Agricultural and Food Chemistry:2011:10(4);2090-7.

Omoni AO, Aluko RE.(2005) The anti-carcinogenic and anti-atherogenic effects of lycopene: a review. Trends in Food Science & Technology;2005:16(8);344-50.

Zhang, D., &Hamauzu, Y.(2004). Phenolic compounds and their antioxidant properties in different tissues of carrots (Daucus carota L.). Journal of Food Agriculture and Environment;2004; 2: 95-100.

Fenko A, Schifferstein HN, Huang TC, Hekkert P.(2009). What makes products fresh: The smell or the colour?. Food Quality and Preference; 2009:20(5);372-9.

Yativ M, Harary I, Wolf S.(2010). Sucrose accumulation in watermelon fruits: genetic variation and biochemical analysis. Journal of plant physiology;2010:167(8);589-96.

Oyewo OO, Onyije FM, Akintunde OW, Ashamu EA.(2012). Effects of aqueous extract of Citrullus lanatus on the histology of the kidney of adult Wistar rats. World Applied Sciences Journal.;2012:17(9);1178-81.

Alberts B .(2012). "Table 22-1 Blood Cells". Molecular Biology of the Cell. NCBI Bookshelf. Archived from the original on 27 March 2018. Retrieved 1 November 2012.

McClatchey, Kenneth D. (2002). Clinical laboratory medicine. Lippincott Williams & Wilkins. pp. 288–. ISBN 978-0-683-30751-1. Retrieved 5 August 2011.

Jamuna, K. S., Ramesh, C. K., Srinivasa, T. R., & Raghu, K. L. (2011). In vitro antioxidant studies in some common fruits. Int J Pharm Pharm Sci. 2011:3(1);60-3.

Alqasoumi SI, Al-Howiriny TA, Abdel-Kader MS.(2008). Evaluation of the hepatoprotective effect of Aloe vera, Clematis hirsute, Cucumis prophetarum and bee propolis against experimentally induced liver injury in rats. International Journal of Pharmacology;2008:4(3);213-7.

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Published

2021-03-17

How to Cite

Ali, S. ., Sultana, N. ., Abbas, M. ., Naz, Z. ., Hassan, M. A. ., & Abid, M. . (2021). Effect Of Citrullus Lanatus Juice On Hemoglobin, Red Blood Cells And Liver Enzyme; An Experimental Study. Journal of Bahria University Medical and Dental College, 9(4), 257–260. https://doi.org/10.51985/JBUMDC2019023

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