Potential Neurological Outcomes in COVID-19 Patients: A Review

Authors

  • Abhishek Lal
  • Mahnoor Khawaja
  • Saleem,
  • Yousuf Ali Lakdawala

DOI:

https://doi.org/10.51985/JBUMDC2020059

Keywords:

Coronavirus, Manifestations, Neurology

Abstract

Coronavirus emerged from Wuhan China, which has been a global challenge for healthcare authorities and individuals.
Patients are presenting to the clinicians with neurological symptoms caused by COVID-19 or with preexisting neurological
conditions with fear of contracting the virus. We have conducted a literature review on neurological outcomes in COVID-
19 patients along with patients with underlying neurological conditions. We searched multiple databases including PubMed,
Google Scholar, EBSCO, Semantic Scholar, and Wiley Online for information on neurological manifestations of patients
suffering from coronavirus. Clinical data and co-morbidities of the patients were examined. Headache, dizziness, hyposmia,
and stroke were among the symptoms reported. Emerging literature is suggesting that coronavirus patients along with
respiratory symptoms are also experiencing neurological symptoms. Some medical emergencies such as stroke require
immediate treatment to save the patients. Neurologists and clinicians need to recognize these symptoms in order to timely
manage and treat the patients

References

Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. Vol. 382, New England Journal of Medicine. 2020. p. 1199–207.

WHO. WHO declares pandemic [Internet]. Available from: https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020

Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020 Mar;579(7798):270–3.

Chen Y, Liu Q, Guo D. Emerging coronaviruses: Genome structure, replication, and pathogenesis. J Med Virol [Internet]. 2020 Apr 7;92(4):418–23. Available from: https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.25681

Wu Y, Xu X, Chen Z, Duan J, Hashimoto K, Yang L, et al. Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain Behav Immun [Internet]. 2020 Jul;87:18–22. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0889159120303573

Gabutti G, D’Anchera E, Sandri F, Savio M, Stefanati A. Coronavirus: Update Related to the Current Outbreak of COVID-19. Infect Dis Ther [Internet]. 2020 Jun 8;9(2):241–53. Available from: http://link.springer.com/10.1007/s40121-020-00295-5

Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet [Internet]. 2020 Feb;395(10223):507–13. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0140673620302117

Wang T, Du Z, Zhu F, Cao Z, An Y, Gao Y, et al. Comorbidities and multi-organ injuries in the treatment of COVID-19. Lancet [Internet]. 2020 Mar;395(10228):e52. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0140673620305584

Chang D, Lin M, Wei L, Xie L, Zhu G, Dela Cruz CS, et al. Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China. JAMA [Internet]. 2020 Mar 17;323(11):1092. Available from: https://jamanetwork.com/journals/jama/fullarticle/2761043

Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, et al.

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Published

2021-03-18

How to Cite

Lal, A. ., Khawaja , M. ., Saleem, & Lakdawala, Y. A. . (2021). Potential Neurological Outcomes in COVID-19 Patients: A Review. Journal of Bahria University Medical and Dental College, 10(4), 310–315. https://doi.org/10.51985/JBUMDC2020059

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Section

Review Article