Arthritis Mutilans: Case Report of an Uncommon Squeal of Psoriatic Arthritis

Authors

  • Farooq Azam Rathore
  • Saeed Bin Ayaz

Keywords:

Rheumatology, Hand deformity, Psoriasis, Arthritis, Joints

Abstract

Psoriatic arthritis (PsA) is a seronegative spondyloarthropathy that presents clinically in different forms. Arthritis mutilans is
a rare yet the most aggressive and disabling form of PsA that requires early diagnosis and aggressive therapy preferably in the
form of biological agents to prevent or stop the irreversible destruction of small joints. We describe here, report of a case of
long standing PsA who developed arthritis mutilans resulting in disability, compromised mobility and a poor quality of life.

References

am. amYoto T. Psoriatic arthritis: from a dermatological perspective. Eur J Dermatol. 2011;21:660-6

Wilson FC, Icen M, Crowson CS, McEvoy MT, Gabriel SE, Kremers HM. Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: a population- based study. Arthritis Rheum. 2009;61(2):233-9 10.1002/ art.24172. Erratum in: Arthritis Rheum. 2010;62(4):574

Cantini F, Piccoli L, Nannini C, Kaloudi O, Bretoni M, Cassarà E.Psoriatic arthritis: a systematic review. Int J Rheum Dis 2010;13:300-17

Dhir V, Aggarwal A. Psoriatic arthritis: a critical review. Clin Rev Allergy Immunol. 2013; 44 (2):141-8

Rodrigues- Moreno J, Bonet M, Blanco-Barnusell J, Castano C, Clavaguera T,Mteo-Soria L, et al. Mutilating/ resorptive arthritis. A study of 24 patients in a series of 360 patients with psoriatic arthritis. Reumatol Clinic 2013;2013:38-41

Bruzzese V, Marrese C, Ridola L, Zullo A. Psoriatic arthritis mutilans: case series and literature review. J

Rheumatol. 2013;40(7):1233-6

Veale DJ. Psoriatic arthritis: recent progress in pathophysiology and drug development. Arthritis Res Ther. 2013;15(6):224

Eder L, Thavaneswaran A, Chandran V, Gladman DD. Tumour necrosis factor blockers are more effective than methotrexate in the inhibition of radiographic joint damage progression among patients with psoriatic arthritis. Ann Rheum Dis. 2014;73(6):1007-11

Gossec L, Smolen JS, Gaujoux-Viala C, Ash Z, Marzo- Ortega H, van der Heijde D, et al. European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Ann Rheum Dis. 2012; 71(1):4-12

Kavanaugh A, McInnes I, Mease P, Krueges GG, Gladman D, Gomez-Reino J, et al. Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: twenty-four-week efficacy and safety results of a randomized, placebo-controlled study. Arthritis Rheum2009;60:976–86

Downloads

Published

2021-03-15

How to Cite

Rathore, F. A. ., & Ayaz, S. B. . (2021). Arthritis Mutilans: Case Report of an Uncommon Squeal of Psoriatic Arthritis. Journal of Bahria University Medical and Dental College, 7(4), 264–266. Retrieved from https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/285

Issue

Section

Case Report