Modifiable Cardiovascular Risk Factors in Adults Less than 40 Years of Age
DOI:
https://doi.org/10.51985/JBUMDC202294Keywords:
Cardiovascular risk factors, Cholesterol, Hypertension, ObesityAbstract
Objectives: To determine the prevalence of modifiable cardiovascular risk factors in adults less than 40 years of age.
Study Design and Setting: A Cross-sectional study was carried out from 2018 to 2019 at University of Sindh, Jamshoro.
Methodology: After getting approval from ethical review board, 263 participants were included in the study using convenient
sampling technique. Subjects over 40 years of age, with history of CVD, who was on medication, pregnant women,
smokers, and drug addicts were excluded. A structured questionnaire was administered, and associated data was collected.
Anthropometric and blood pressure measurements were made. Blood was drawn and analysed for total cholesterol, LDL,
triglycerides, HDL, and blood sugar. The existence of modifiable risk variables is shown as percentages, and the difference
between genders was evaluated using the chi-square test.
Results: Out of total subject, 76% had at least one risk factor present. The risk of Obesity was 29% and 30% for men and
women respectively. Central obesity was higher in females (61%) as compared to males (35). Risk factors including
hypertension, total triglycerides, and less-than-desired high-density lipoprotein were more prevalent in males as compared
to females (p-value .0001). Whereas risk factors including total cholesterol and inactive lifestyle were more in females as
compared to males (p-value 0.012 & .0007respectively).
Conclusion: Three risk factors (Obesity, Central obesity, and Total Cholesterol) were found to be higher in females, while
4 risk factors (Hypertension, Increased TG, raised LDL, and hyperglycemia) were higher in males.
References
World Health Organization. Cardiovascular diseases. (2017).
Accessed: August 15, 2018: http://www.who.int/mediacentre/
factsheets/fs317/en/index.html.
World Health Organization. Cardiovascular diseases. (2021).
Accessed: June 11, 2021: https://www.who.int/en/newsroom/fact-sheets/detail/cardiovascular-diseases-(cvds).
Shahid SU, Sarwar S. The abnormal lipid profile in obesity
and coronary heart disease (CHD) in Pakistani subjects. Lipids
Health Dis. 2020; 19(1): 1-7. DOI: https://doi.org/ 10.1186/
s12944-020-01248-0.
Aminde LN, Dzudie A, Mapoure YN, Tantchou JC, Veerman
JL. Estimation and determinants of direct medical costs of
ischaemic heart disease, stroke and hypertensive heart disease:
evidence from two major hospitals in Cameroon. BMC Health
Serv Res. 2021; 21(1): 1-3. DOI: https://doi.org/ 10.1186/
s12913-021-06146-4.
Þahin B, Ýlgün G. Risk factors of deaths related to cardiovascular diseases in World Health Organization (WHO) member
countries. Health Soc Care Community. 2022; 30(1): 73-80.
DOI: https://doi.org/ 10.1111/hsc.13156.
Drozdz D, Alvarez-Pitti J, Wójcik M, Borghi C, Gabbianelli
R, Mazur A, Herceg-Èavrak V, Lopez-Valcarcel BG, Brzeziñski
M, Lurbe E, Wühl E. Obesity and cardiometabolic risk factors:
From childhood to adulthood. Nutrients. 2021; 13(11): 4176-
DOI: https://doi.org/ 10.3390/nu13114176.
Þahin B, Akþan ÝO, Önal BS, Hoþoðlu E, Karabekiroðlu K.
Evaluation of carotid intima media thickness as an early marker
of atherosclerosis in children and adolescents with autism
spectrum disorder: a case-control study. Int J Dev Disabil.
; 30: 1-0.
Drogalis-Kim D, Cheifetz I, Robbins N. Early nutritional
influences of cardiovascular health. Expert Rev Cardiovasc
Ther. 2021; 19:12: 1063-73. DOI: https://doi.org/ 10.1080/
2021.2021070.
Francula-Zaninovic S, Nola IA. Management of measurable
variable cardiovascular disease'risk factors. Curr Cardiol Rev.
; 1;14(3): 153-63. DOI: https://doi.org/.2174/ 1573403
X14666180222102312.
Yusuf S, Joseph P, Rangarajan S, Islam S, Mente A, Hystad
P, Brauer M, Kutty VR, Gupta R, Wielgosz A, AlHabib KF.
Modifiable risk factors, cardiovascular disease, and mortality
in 155 722 individuals from 21 high-income, middle-income,
and low-income countries (PURE): a prospective cohort study.
The Lancet. 2020; 395(10226): 795-808. DOI: https://doi.org/
1016/S0140-6736(19)32008-2.
Saleheen D, Frossard P. CAD risk factors and acute myocardial
infarction in Pakistan. Acta Cardiol. 2004; 59(4): 417-24. DOI:
https://doi.org/ 10.2143/AC.59.4.2005208.
Nanan DJ. The obesity pandemic--implications for Pakistan.
J Pak Med Assoc. 2002; 52(8): 342-46.
Noor M, Raza UA, Zeeshan MF, Mohammad W. Frequency
of abnormal waist circumference and associated risk factors
in healthy adults. J Pak Med Assoc. 2007; 21(4): 248-255.
Javed A, Saleem S, Saeed M, Raza H, Shahid B, Islam K.
Influence of Socio-demographic Variables on Prevalence of
Hypertension in Lahore Division, Pakistan. American Academic
Scientific Research Journal for Engineering, Technology, and
Sciences. 2021; 81(1): 186-91.
Dal Canto E, Ceriello A, Rydén L, Ferrini M, Hansen TB,
Schnell O et al. Diabetes as a cardiovascular risk factor: an
overview of global trends of macro and microvascular complications. Eur J Prev Cardiol. 2019; 26(2): 25-32. DOI:
https://doi.org/ 10.1177/2047487319878371.
Khan HU, Khan I, Khan AA, Rahman AU, Khan Z, Khan RU.
Lipid profile in type 2 diabetics versus non-diabetic controls
in adult population of district Bannu, Pakistan. Gomal j. med.
sci. 2022; 20(1): 17-23.
Barnett TA, Kelly AS, Young DR, Perry CK, Pratt CA,
Edwards NM et al. American Heart Association Obesity
Committee of the Council on Lifestyle and Cardiometabolic
Health; Council on Cardiovascular Disease in the Young; and
Stroke Council. Sedentary behaviors in today’s youth: approaches to the prevention and management of childhood
obesity: a scientific statement from the American Heart
Association. Circulation. 2018;138(11): e142-59. DOI: https://doi.org/ 10.1161/CIR.0000000000000591.
Mainous III AG, Tanner RJ, Rahmanian KP, Jo A, Carek PJ.
Effect of sedentary lifestyle on cardiovascular disease risk
among healthy adults with body mass indexes 18.5 to 29.9
kg/m2. Am J Cardiol. 2019; 123(5): 764-68. DOI: https://
doi.org/ 10.1016/j.amjcard.2018.11.043.
Hayes L, White M, Unwin N, Bhopal R, Fischbacher C,
Harland J, Alberti KG. Patterns of physical activity and
relationship with risk markers for cardiovascular disease and
diabetes in Indian, Pakistani, Bangladeshi and European adults
in a UK population. J Public Health. 2002; 24(3): 170-8. DOI:
https://doi.org/ 10.1093/pubmed/24.3.170.
Irfan M, Jabbar M, Hameed S. Dietary Habits and
Prevalence of Underweight/ Obesity in Students of
University of Gujrat, Pakistan. J Liaquat Uni Med Health
Sci. 2019;18(02):175-80. DOI: https://doi.org/ 10.22442/
jlumhs.191820623.
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