Naegleria fowleri - Simple Facts About Brain Eating Amoeba

Authors

  • Irfan Ali Mirza

Abstract

Year after year, the inhabitants of Karachi have to face the fear and panic of Naegleria fowleri which can cause deadly disease called meningoencephalitis. A common citizen remains extremely wary of what to do and what not to do. The health authorities do come up with awareness campaigns mounted on large sized billboards, yet the simple facts remains eluded to even majority of health care personnel. It was in 1958 that Culbertson and his colleagues first described the concept that free living soil and water amoebae can cause disease in humans. Since then number of fatal cases of acute meningoencephalitis have been reported.1 Naegleria is a free living amoeba, commonly found in warm freshwater for example, lakes, rivers, hot springs and soil. Only one of the specie of Naegleria known as Naegleria fowleri is pathogenic and infects humans. This parasite infects people when water containing the amoeba enters the body through the nose. This normally occurs when people swim or dive in warm freshwater places, like lakes and rivers. The amoeba then travels up the nose to the brain via olfactory nerve where it destroys the brain tissue.2 As this amoeba can be found in warm freshwater, such as lakes and rivers, swimming pools that are poorly maintained, minimally chlorinated, and/or un-chlorinated, so the recreational water users should be aware that there will always be a low level risk of infection when entering these waters

References

Schuster FL, Visvesvara GS. Free living amoebae as opportunistic and non –opportunistic pathogens of humans and animals. Int J Parasitol 2004; 34: 1001-27.

Garcia LS. Free living amoebae. In: Diagnostic Medical Microbiology. 5th Ed. ASM press;2007 p102-22

Phu NH, Hoang Mai NT, Nghia HD, Chau TT, Loc PP, Thai l H. Fatal consequences of freshwater pearl diving. Lancet. 2013; 381:176.

Gautam PL, Sharma S. A rare case of survival from primary amebic meningoencephalitis. Indian Crit Care Med 2012; 16:34-6.

Hebbar S, Bairy I .Fatal case of Naegleria fowleri meningo-encephalitis in an infant .Ann Trop Paediatr 2005; 25:223-6.

ShariqA, Afridi FI, Farooqi BJ, Ahmed S, Hussain A. Fatal primary meningoencephalitis caused by Naegleria fowleri. J Coll Physicians Surg Pak 2014; 24:523-5.

Kim JH, Yang AH, Sohn HJ, Kim D, Song KJ, Shin HJ. Immunodominant antigens in Naegleria fowleri excretory secretory proteins were potential pathogenic factors. Parasitol Res 2009; 105:1675-81.

Center for Disease Control and Prevention. Primary amoebic meningoencephalitis--Arizona, Florida, and Texas, 2007. MMWR Morb Mortal Wkly Rep. 2008; 57(21):573-7.

Vargas-Zepeda J, Gomez-Alcala AV, Vasquez-Morales JA, Licea-Amaya L, De Jonckheere JF, Lares-Villa F. Successful treatment of Naegleria fowleri meningoencephalitis by using intravenous amphotericin B, fluconazole and rifampicin. Arch Med Res 2005;36:83-6

Shakoor S, Beg MA, Mahmood SF, Bandea R, Sriram R, Noman F. Primary amoebic meningoencephalitis caused by Naegleria fowleri, Karachi, Pakistan. Emerg Infect Dis. 2011; 17:258-61.

Downloads

Published

2015-03-10

How to Cite

Mirza, I. A. . (2015). Naegleria fowleri - Simple Facts About Brain Eating Amoeba. Journal of Bahria University Medical and Dental College, 5(1), 1–2. Retrieved from https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/90