Ageing ovaries and endometrium in PCOS
Keywords:
Polycystic ovaries, hyperandrogenism, infertility, ovarian volume, follicle count, follicle size, uterine area and endometrial thickness.Abstract
Objective: to measure the outcome of age on ovarian and uterine morphology in women with primary infertility due to polycystic ovarian syndrome (PCOS) Materials and Methods: It was an observational cross sectional study. Two hundred primary infertile women with PCOs were subdivided into age groups (years) 20-30 (group I) and 31- 40 (group II). The ovarian volume (OV), follicles count (FC) and size (FS), uterine area (UA) and endometrial thickness (Endo) were determined by trans- abdominal (TAS) and trans -vaginal scan (TVS) using the ultrasound machine. Unpaired t-test was applied to evaluate the result Results: Comparison between group I and group II was made to evaluate the outcome. A significant raise was noted in the uterine morphology of group II. The UA was 89.99±5.83 v/s 119.0±23.33 (0.001) and endometrial thickness was 0.48±0.11 v/s 0.59±0.13 (0.001). A significant decline was noted in the ovarian morphology of group II; the OV (TAS) was 15.36± 2.56 v/s 10.57±12 (0.001) and TVS showed 15.74±2.23 v/s 10.37±1.08 (0.001). The FC was 14.05±1.56 v/s 12.47±0.89 (0.022) and FS was 9.45±7.98 v/s 4.33±5.88 (0.00). Conclusion: The OV, FC and FS (ovarian morphology) variables decreases in the elder infertile group with PCOs but the uterine morphology variables showed an increase in area with thickening of endometrium in the elder group.
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