To Evaluate Povidone-iodine Effect On Post Appendectomy Surgical Site Infection
DOI:
https://doi.org/10.51985/JBUMDC2018024Keywords:
Surgical site infection, Povidone-Iodine, AppendectomyAbstract
Objective: Evaluating the effects of Povidone- Iodine against the surgical site infection in post- appendectomy wound
infection.
Study design: Randomized clinical trial
Place and duration: Department of Surgery, Isra University Hospital Hyderabad from January 2016 to December 2017.
Subjects and Methods: Patients of acute appendicitis with classical clinical presentation were selected according to
inclusion and exclusion criteria. 60 patients were those in which wound was irrigated with 1% povidone-iodine solution
versus 60 patients in whom wound not irrigated with it before skin closure. Data was analyzed on SPSS 22.0 using Student
t-test and Chi- square test respectively. Data was analyzed at 95% confidence interval (P=0.05). P-value of =0.05 was taken
statistically.
Results: Mean ± SD age of control and cases was noted as 22.5 ± 7.5 and 23.5 ± 6.5 years respectively (P=0.86). Male
and female population in control and cases were noted as 45 (75%) and 15 (25%) & 47 (78.33%) and 13 (21.66%)
respectively (P >0.05). Grade 4 pus discharging wound infection was noted in 3.33% in control compared to 1.66% in cases
(P= 0.87). Normal wound healing (grad 0) was noted in 37 (61.6%) and 43 (71.6%) of control and cases respectively. In
control grade 1-4 lesions were noted in 38.4% compared to 28.4% in cases (P < 0.05).
References
Parthiban N, Harish M. A study on microbiology culture of
acute appendicectomy specimen and its correlation with
wound infection. Int Surg J 2017;4 :2212-5.
Jan Y. Comparison of postoperative wound infection in open
versus laparoscopic appendectomy. Rawal Med J 2014; 39:55-
Khan MN, Fayyad T, Cecil TD, Moran BJ. Laparoscopic versus Open Appendicectomy: the risk of postoperative infectious
complications. J Soc Laparos Surg 2007; 11:363-7
Mughal SA, Soomro S. Acute appendicitis in children. J Surg
Pak 2007; 12:123-5.
Perveen S, Sarwar G, Saeed N, Channa GA. Laparoscopic
versus open appendicectomy as an elective procedure. Med
Channel 2007; 13:18-20.
Selvaggi G, Monstrey S, Vanlanduyt K, Hamdi M, Blondeel
P. The role of iodine in antisepsis and wound management:
a reappraisal. Acta Chir Belg 2003; 103:241-7.
Nishimura C. Comparison of the antimicrobial efficacy of
povidone-iodine, povidone-iodine-ethanol and chlorhexidine
gluconate-ethanol surgical scrubs. Dermatology 2006; 212:21-
Cheng MT, Chang MC, Wang ST, Yu WK, Liu CL, Chen TH.
Efficacy of dilute betadine solution irrigation in the prevention
of post operative infection of spinal surgery. Spine 2005;
:1689-93.
Harihara Y, Konishi T, Kobayashi H, Furushima K, Ito K,
Noie T, et al. Effect of applying povidone-iodine just before
skin closure. Dermatology 2006; 212:53-7.
Drousou A, Falabella A, Kirsner RS. Antiseptics on wounds:
an area of controversy. Wounds 2003; 15:149-66.
Chang FY, Chang MC, Wang ST, Yu WK, Liu CL, Chen TH.
Can povidone-iodine solution be used safely in a spinal
surgery? Eur Spine J 2006; 15:1005-14.
Iqbal M, Jawaid M, Qureshi A, Iqbal S. Effect of povidoneiodine irrigation on post appendectomy wound infection:
randomized control trial. J Postgrad Med Inst 2015; 29(3):
-4.
Arshad M, Aziz LA, Qasim M, Talpur KA. Early appendicectomy in appendicular mass: a Liaquat University hospital
experience. J Ayub Med Coll Abottabad 2008; 20:70-2.
Kouwenhoven EA, Repelaer van Driel OJ, van Erp WF. Fear
for the intra-abdominal abscess after laparoscopic appendectomy: not realistic. Surg Endosc 2005; 19:923-36.
Shah SA. Laparoscopic appendicectomy versus conventional
open appendicectomy: A study at Lahore General Hospital.
Esculapio J Services Inst Med Sci 2008; 3:21-24.
Ahmad N, Abid KJ, Khan AZ, Shah STA. Acute Appendicitis-Incidence of Negative Appendicectomies. Ann King
Edward Med Coll 2002; 8:32-4.
Chaudhary IA, Samiullah MAA, Afridi Z, Bano A. Is it necessary to invaginate the stump after appendicectomy? Pak J
Med Sci 2005; 21:35-8.
Koederitz NM, Neely DE, Plager DA, Boehmer B, Ofner S,
Sprunger DT et al. Postoperative povidone-iodine prophylaxis
in strabismus surgery. J AAPOS 2008; 12:396-400.
Pattana-arun J, Wolff BG. Benefits of povidone-iodine solution
in colorectal operations: science or legend. Dis Colon Rectum
; 51:966-71.
Shindo K, Funai S, Kuroda K, Wakano T, Nishimura K.
Clinical study on the antiseptic effect of povidone-iodine
solution for the surgical field of digestive tract operations.
Dermatology 2002; 204:47-51
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Copyright (c) 2018 Rizwanullah Junaid Bhanbhroq, Khalil Ahmed Almani, Sadia Kazi, Navaid Kazi, Sumayya Kazi
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