Medical Marijuana: A Hope For Resistant Epilepsy?
DOI:
https://doi.org/10.51985/JBUMDC2019069Abstract
Dear sir,
Cannabis is a popular recreational drug worldwide and
recently has been approved by many countries and a few
states within the USA for recreational purposes. It is
composed of two basic components, the psychoactive part
tetrahydrocannabinol (THC) that targets CB1 and CB2
receptors in the body and counteracts reactive oxygen species
and the Cannabinoidiol (CBD) component is famous for its
medicinal use that works without interacting with these
receptors and is free of psychiatric side effects.
References
Borgelt LM, Franson KL, Nussbaum AM, Wang GS (February 2013). "The pharmacologic and clinical effects of medical cannabis". Pharmacotherapy(Review). 33 (2): 195–209.
Maroon J, Bost J. Review of the neurological benefits of phytocannabinoids. Surg Neurol Int. 2018;9:91. Published 2018 Apr 26. doi:10.4103/sni.sni_45_18
I. A. Khatri, S. T. Iannaccone, M. S. Ilyas, M. Abdullah, S. Saleem Epidemiology of epilepsy in Pakistan: review of literature J Pak Med Assoc. 2003; 53(12): 594–597.
O'Connell, B. K., Gloss, D., & Devinsky, O. (2017). Cannabinoids in treatment-resistant epilepsy: a review. Epilepsy & Behavior, 70, 341-348.
Zaheer, S., Kumar, D., Khan, M. T., Giyanwani, P. R., & Kiran, F. N. U. Epilepsy and Cannabis: A Literature Review. Cureus, 2018; 10(9).
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Copyright (c) 2019 Arsalan Anwar, Sidra Saleem
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