Ocular Syphilis – Uncommon but not Rare
Keywords:
Ocular Syphilis, Uveitis, Panuveitis, NeurosyphilisAbstract
Syphilis is a multisystem bacterial infection caused by the spirochete TreponemaPallidum, which has regained attention as a
new epidemic due to worldwide increase in the cases of this disease. Ocular syphilis is an unusual manifestation of disease,
mostly occurring in the secondary or tertiary stage of disease. Ocular involvement may be the presenting manifestation of
syphilis and it is often associated with delayed diagnosis and treatment, which may result in irreversible structural and functional
ocular damage. Although, ocular syphilis can affect any part of eye, uveitis is the most common ocular manifestation of the
disease. A high index of suspicion is mandatory as ocular syphilis can mimic variety of other ocular inflammations. We report
two cases of syphilitic panuveitis where high index of suspicion resulted in the correct diagnosis and management.
References
Pichi F, Ciardella AP, Cunningham ET. Jr , Morara M,
Veronese C, Jumper JMet al. Spectral domain optical
coherence tomography findings in patients with acute
syphilitic posterior placoid chorioretinopathy. Retina
; 34 (2):373-84
Mathew RG, Goh BT, Westcott MC. British Ocular Syp-
hilis Study(BOSS): 2-year national surveillancestudy
of intraocular inflammation secondaryto ocular syphilis.
Invest Ophthalmol Vis Sci 2014; 55:(5)394-400
Wahab AA, Rahman MM, Mohammad M, Hussin S.
Case series of syphilis and HIV co-infections. Pak J
Med Sci 2013; 29(3):856-8
Benson CE, Soliman MK, Knezevic A, Xu DD, Nguyen
QD, Do DV. Bilateral papillitis and unilateral focalchori-
oretinitis as the presenting features of syphilis.J Ophthal-
mic Inflamm Infect 2015; 5:16 doi: 10.1186/s12348-
-0045-0
Lutchman C, WeisbrodDJ, Schwartz CE. Diagnosis and
management of syphilis after unique ocular presentation.
Can Fam Physician 2011; 57:896-9
Hong MC, Sheu SJ, Wu TT, Chuang CT. Ocular uveitis
as the initial presentation of syphilis. J Chin Med Assoc
; 70(7):274-80
Pan SW, Yusof NS, Hitam WHW, Noor RAM, Embong
Z. Syphiliticuveitis: report of 3 cases. Int J Ophthalmol
; 3(4):361-4
Birnbaum AD, Little DM, Tessler HH,Goldstein DA.
Etiologies of chronic anterior uveitis at a tertiary referral
center over 35 Years. OculImmunolInflamm 2011; 19(1)
:19-25
Anshu A, Cheng CL, Chee SP: Syphilitic uveitis: an
Asian perspective. Br J Ophthalmol 2008; 92:594-7
Amaratunge BC, Camuglia JE, Hall AJ. Syphilitic uveitis:
a review ofclinical manifestations and treatment outcomes
of syphilitic uveitis inhuman immunodeficiency virus-
positive and negative patients. ClinExpOphthalmol 2010
(1):68-74
Awais M, Zafar O. Syphilitic Uveitis: A Therapeutic
Challenge. Pak Armed Forces Med J 2012; 62(3): 464-6
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Copyright (c) 2015 Qamar Ul Islam, Dilshad Ali
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