Association between Intraocular Pressure and Myopia Among Children Aged 7 to 16 years

Authors

  • Arooshia Shahzadi
  • Maryam Firdous
  • Fareeha Ayyub
  • Sadaf Qayyum
  • Saif ullah
  • Rabeeah Zafar

DOI:

https://doi.org/10.51985/JBUMDC2023165

Keywords:

Emmetropia, Glaucoma, Intra-ocular pressure, Myopia

Abstract

Objectives: To investigate the association between high intraocular pressure and myopia in children and compare it to
emmetropia, and to determine the relationship between elevated intraocular pressure and varying degrees of myopia.
Study design and Setting: Comparative cross-sectional study was performed at the tertiary eye care hospital, Rawalpindi
for six months from July 2021 to December 2021.
Methodology: Patients with myopia of greater than 0.5Ds and emmetropes with visual acuity of 6/6 were included. All
patients underwent visual acuity, cycloplegic refraction, and fundus examination in order to exclude the myopic patientswith
other systemic and ocular disorders. Intraocular pressure and central corneal thickness were measured using a Tonopen
tonometer and Pachymeter respectively.Data was entered on SPSS version 26 for analysis. Independent sample T-test and
one-way ANOVA was utilized for inferential statistics.
Results: A total of 218 subjects were included with a mean age of 11.38 ± 2.602 ranging from 7 to 16 years. Females
50.9% (n=111) were outnumbered by male participants 49.1% (n=107). The mean IOP in emmetropes was 13.35 ± 2.433
mmHg and in myopes was 15.22 ± 3 mmHg and there is a statistically significant mean difference between these groups
(P-value <0.05). There is also a statistically significant mean difference between IOP and varying degrees of myopia, that
is; low(13.46 ±2.797), moderate(16.62 ± 2.981), and high(19.215 ± 2.184).
Conclusions: The IOP was higher in high and moderate myopic eyes as compared to emmetropes. Moreover, a strong
association was found between myopia and elevated IOP in children.

References

Dutheil F, Oueslati T, Delamarre L, Castanon J, Maurin C,

Chiambaretta F, Baker JS, Ugbolue UC, Zak M, Lakbar I,

Pereira B. Myopia and near work: a systematic review and

meta-analysis. International Journal of Environmental Research

and Public Health. 2023;20(1):875. https://doi.org/10.3390%

Fijerph20010875

Cumberland PM, Bountziouka V, Rahi JS. Impact of varying

the definition of myopia on estimates of prevalence and

associations with risk factors: time for an approach that serves

research, practice and policy. British Journal of Ophthalmology.

;102(10):1407-12. https://doi.org/10.1136%

Fbjophthalmol-2017-311557

Sankaridurg P, Tahhan N, Kandel H, Naduvilath T, Zou H,

Frick KD, Marmamula S, Friedman DS, Lamoureux E, Keeffe

J, Walline JJ. IMI impact of myopia. Investigative

ophthalmology & visual science. 2021;62(5):2-. https://doi.org/

1167/iovs.62.5.2

Sapkota YD, Adhikari BN, Pokharel GP, Poudyal BK, Ellwein

LB. The prevalence of visual impairment in school children

of upper-middle socioeconomic status in Kathmandu.

Ophthalmic epidemiology. 2008;15(1):17-23. https://doi.org

/10.1080/09286580701772011

Agarwal D, Saxena R, Gupta V, Mani K, Dhiman R, Bhardawaj

A, Vashist P. Prevalence of myopia in Indian school children:

meta-analysis of last four decades. PloS one. 2020;15(10)

:e0240750.https://doi.org/10.1371/journal.pone.0240750

Sirang Z, Nanji K, Jeeva IK, Khan ZW, Kazmi HS. Types of

refractive errors in northern Pakistan: A hospitalbased survey.

Ophthalmology J. 2019; 4:86-91.

Wang YX, Yang H, Wei CC, Xu L, Wei WB, Jonas JB. High

myopia as risk factor for the 10-year incidence of open-angle

glaucoma in the Beijing Eye Study. British Journal of

Ophthalmology. 2023;107(7):935-40. https://doi.org/10.1136/

bjophthalmol-2021-320644

Barros D, Moura JC, Freire CR, Taleb AC, Valentim RA,

Morais PS. Machine learning applied to retinal image

processing for glaucoma detection: review and perspective.

Biomedical engineering online. 2020;19(1):1-21.

Zhang N, Wang J, Li Y, Jiang B. Prevalence of primary open

angle glaucoma in the last 20 years: a meta-analysis and

systematic review. Scientific reports. 2021;11(1):13762.

Machiele R, Motlagh M, Patel BC. Intraocular Pressure. In:

StatPearls. StatPearls Publishing, Treasure Island (FL); 2022.

PMID: 30335270.

Latif MZ, Khan MA, Afzal S, Gillani SA, Chouhadry MA.

Prevalence of refractive errors; an evidence from the public

high schools of Lahore, Pakistan. JPMA. 2019;69(464).

BaezaMoyano D, González-Lezcano RA. Pandemic of

Childhood Myopia. Could New Indoor LED Lighting Be Part

of the Solution?. Energies. 2021;14(13):3827. https://doi.org/

3390/en14133827

Nadeem S, Naeem BA, Tahira R, Khalid S, Hannan A.

Comparison of Goldmannapplanation, Diatontranspalpebral

and Air Puff tonometers. Pak J Ophthalmol. 2015 ;31(1).

Acharlu PB, MK PR, Srivastava VK. A Study on Association

between Intraocular Pressure and Myopia. Journal of Evolution

of Medical and Dental Sciences. 2020;9(18):1500-4.

14260/jemds/2020/327

Lee AJ, Saw SM, Gazzard G, et al. Intraocular pressure

associations with refractive error and axial length in children.

Br J Ophthalmol 2004;88(1):5-7. https://doi.org/ 10.1136

/bjo.88.1.5

Sun MT, Tran M, Singh K, Chang R, Wang H, Sun Y.

Glaucoma and Myopia: Diagnostic Challenges. Biomolecules.

;13(3):562. https://doi.org/10.3390/biom13030562

Sharma B. Comparison of intraocular pressure variance in

moderate and high myopia. European Journal of Molecular

& Clinical Medicine.;7(2):2020.

Shim SH, Sung KR, Kim JM, Kim HT, Jeong J, Kim CY,

Lee MY, Park KH. The prevalence of open-angle glaucoma

by age in myopia: the Korea national health and nutrition

examination survey. Current Eye Research. 2017;42(1):65-

https://doi.org/10.3109/02713683.2016.1151053

Han X, Yang T, Zhang J, Yu S, Guo X, Yan W, Hu Y, He M.

Longitudinal changes in intraocular pressure and association

with systemic factors and refractive error: Lingtou Eye Cohort

Study. BMJ open. 2018 Feb 1;8(2):e019416.

Joseph DS, Thampi B, Joosadima A, Mohan A. A study on

association between intraocular pressure and myopia. Int J

Res Med Sci. 2017;4(6):2202-5. https://doi.org/10.18203/2320-

ijrms20161786

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Published

2023-07-13

How to Cite

Shahzadi, A. ., Firdous, M. ., Ayyub, F. ., Qayyum, S. ., ullah, S., & Zafar, R. . (2023). Association between Intraocular Pressure and Myopia Among Children Aged 7 to 16 years. Journal of Bahria University Medical and Dental College, 13(03), 197–200. https://doi.org/10.51985/JBUMDC2023165

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Original Articles