Obstetric Restless Legs Syndrome in Industrialized Area of Pakistan

Authors

  • Atiya Fasih
  • Khalida Nasreen Abdullah
  • Samreen Iqbal

Keywords:

Obstetrics restless legs syndrome, Frequency, Industrialized area, Risk factors

Abstract

Objective:To determine the frequency of obstetrics Restless legs syndrome(RLS) in industrialized area of Karachi and to identify
possible risk factors of RLS in Pakistani population.
Materials and Methods:This cross-sectional study was carried out in a Teaching Hospital from 1st January 2013 to 31st January
2014.All pregnant women of 20- 44 years old in first trimester without peripheral vascular disease, painful legs, peripheral
neuropathy, nocturnal leg cramps and moving toes were enrolled in the study. A close-ended questionnaire developed from
International RLS Study Group was used.The diagnosis of RLS was then ascertained by the obstetrician by using the criteria
of the International RLS Study Group and they were labeled as “RLS sufferers and were kept in RLS group while others that
is non RLS sufferers were kept in the healthy group. Descriptive and comparative statistical analyses were performed using
SPSS Statistical Software 17.
Results:During a period of thirteen months, 900 pregnant women were interviewed and examined out of these 85.7% fulfilled
the criteria and constituted the study population. Out of these 31.90 % were RLS suffers. Among RLS suffers 55% were resident
of industrialized area. The majority of RLS suffers were multigravida and in their advance pregnancies.
Conclusion: The frequency of obstetrics Restless legs syndrome (RLS) in industrialized area of Karachi is 31.90 % Possible
risk factors of RLS in Pakistani population are multigravidity, advance pregnancy, industrialized area etc.

References

National Heart, Lung and Blood Institute Working Group on restless legs syndrome. Restless legs syndrome: detection and management in primary care. American Family Physician Journal. 2000; 1(62): 108-14.

Neau JP, Texier B, Ingrand P: Sleep and vigilance disorders

in pregnancy. EurNeurol 2009; 62: 23–9.

Pien GW, Schwab RJ: Sleep disorders during pregnancy.

Sleep 2004; 27: 1405–17.

Manconi M, Govoni V, De Vito A. Pregnancy as a risk factor for restless legs syndrome.Sleep Med 2004; 5: 305–8.

Sikandar R, Khealani BA, Wasay M: Predictors of restless legs syndrome in pregnancy: a hospitalbased rosssectional

survey inPakistan. Sleep Med 2009; 10: 676–8.

Richard P. Allen , Daniel L. Picchietti , Diego GarciaBorre-guero , William G. Ondo , Arthur S. Walters , John W. Wink-elman et.al. The International Restless Legs Syndrome Study Group Published Online: May 16, 2014

Facco FL, Kramer J, Ho KH, Zee PC, GrobmanWA: Sleep disturbances in pregnancy. ObstetGynecol 2010; 115: 77 –83.

Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J. Restless Legs Syndrome Diagnosis and Epidemiology workshop at the National Institutes of Health; International Restless Legs Syndrome Study Group. Restless legs syndrome: diagnostic criteria, special consi-derations, and epidemiology: a report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003; 4:101-9.

Ekbom KA. 1945. Restless legs: a clinical study. ActaMedic-aScandSuppl, 158:1-6

Ekbom KA: Restless legs syndrome. Acta Med Scand 19 45; 158(suppl):4–122.

Mussio-Fournier JC, Rawak F: FamiliäresAuftreten von Pruritus, Urtikaria und parasthetischerHyperkinese der unterenExtremitäten. Conf Neurol1940; 3: 110–4.

Jolivet B: Paresthésies nocturnes agitantesdesmembres-inférieurs; thèse de Médecine, Paris 1953.

Ekbom K: Acroparesthesia and restless legs in pregnancy.

Sven Lakartidn1960; 57: 2597–603.

Goodman JD, Brodie C, Ayida GA: Restless leg syndrome in pregnancy. BMJ 1988; 297:1101–2.

Suzuki K, Ohida T, Sone T: The prevalence of restless legs syndrome among pregnantwomen in Japan and relationship between restless legs syndrome and sleep problems. Sleep 2003; 26: 673–7.

Manconi M, Govoni V, De Vito A: Restless legs syndrome and pregnancy. Neurology2004; 63:1065–9.

Tunc T, Karadag YS, Dogulu F, Inan LE: Predisposing factors of restless legs syndrome in pregnancy. Mov Dis 2007; 22: 627–31.

Herraiz de Castro C, Martinez FG, Angulo AMB, Alejo MA: Sindrome de laspiernasinquietasen elembarazo. AtenPrimaria 2007; 39: 625–6.

Wesström J, Skalkidou A, Manconi M, et al. Pre pregnancy restless legs syndrome (Willis-Ekbom Disease) is associated with perinatal depression. J Clin Sleep Med 2014; 10:527.

Facco FL, Kramer J, Ho KH, Zee PC, Grobman WA: Sleep disturbances in pregnancy.Obstet Gynecol 2010;115: 77–83.

Picchietti DL, Hensley JG, Bainbridge JL. Consensus clinical practice guidelines for the diagnosis and treatment of restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation. Sleep Med Rev 2015; 22:64.

Berger K, Luedemann J, Trenkwalter C, John U, Kessler C: Sex and the risk of restless legssyndrome in the general population. Arch Intern Med 2004;164: 196–202.

Philips B, Young T, Finn L: Epidemiology of restless legs syndrome in adults. ArchIntern Med 2000; 160: 2137–41.

Pantaleo NP, Hening WA, Allen RP, Earley CJ: Pregnancy accounts for most of the genderdifference in prevalence of familial RLS. Sleep Med 2010; 11:310–13.

Ghorayeb I, Bioulac B, Scribans C, Tison F: Perceived severity of restless legs syndrome across the female life cycle. Sleep Med 2008; 9: 799–802

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Published

2015-06-04

How to Cite

Fasih, A. ., Abdullah, K. N. ., & Iqbal, S. . (2015). Obstetric Restless Legs Syndrome in Industrialized Area of Pakistan. Journal of Bahria University Medical and Dental College, 5(2), 69–72. Retrieved from https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/114

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