Abstract:
Dengue virus is an endemic disease which has great public health significance in terms of
morbidity and mortality. The disease has recently had major epidemics in most tropical and sub
tropical areas with an estimated 50 to 100 million cases of Dengue fever and about half a million
cases of Dengue hemorrhagic /Dengue shock syndrome worldwide every year, Dengue is now
recognized as one of the major public health concerns globally