Abstract:
Objective: To determine the association of Vitamin D deficiency with peripheral neuropathy in patients of type-2 Diabetes
mellitus.
Study Design and Setting: It was a cross sectional study conducted in a private clinic in Karachi, during a period of three
months.
Methodology: Total of 70 cases were included according to inclusion and exclusion criteria. Approval was sought from
Ethical review committee. Consent was signed from the patients before the data collection. All the patients who were
coming to the clinic, 30-75years of age, had history of type 2 diabetes for more than 5 year with HbA1c of 7% or above
and had peripheral neuropathy were included. Data was collected in a pre-designed proforma. For entry of data and its
statistical analysis SPSS version 20 was used.
Results: From the total 70 cases n=41(58.5%) were vit D deficient. Most of the patients with type 2 diabetes with neuropathy
were in the age group of 61-75yrs (57%) followed by 46- 60yrs age group (30 %). This study also showed that 30 females
(73%) and 11 males (26.8 %) were deficient in vitamin D.
Conclusion: Type 2 diabetic patients with vitamin D deficiency were more at risk of developing diabetic peripheral
neuropathy (DPN) earlier. It is required to supply vitamin D appropriately for preventing DPN in type 2 diabetes.