Abstract:
Objective: To determine effect of citrullus lanatus juice on hemoglobin and Serum Glutamic Pyruvic Transaminase (SGPT)
level.
Study design and setting: It was an experimental study conducted on healthy rabbits for sixty days in the research
department of pharmacy University of Karachi.
Methodology: Current study was planned to evaluate effect of Citrullus lanatus juice on red blood cells, hemoglobin and
liver enzyme. 60 days study was performed at 2 different doses i.e 3and 6ml/kg on rabbits. These rabbits were from either
gender and were divided into 3 groups their weight ranges from 1200 to 1800 grams. Group A is control group (Normal
saline 6ml/kg), Group B is treated group (3 ml/kg), Group C is treated group (6ml/kg). After taking mean of all values they
are compared with control group. Significance of mean can be estimated by Tukes Post Hoc Test. P<0.05 estimated as
significant.
Results: It was found that count of red blood cells rises significantly along with rise in hemoglobin level. As far as liver
enzyme serum glutamate pyruvate transaminase (SGPT) was concerned its concentration decreases slightly.
Conclusion: Citrullus lanatus juice contain ingredients which are important for RBC hemoglobin and synthesis .It also
contains important antioxidants that have organoprotective role due to which SGPT level decreases even in healthy animals
as compared to control groups.