TY - JOUR AU - Ahmed, Sanaa AU - Nasir, Muhammad AU - Khan, M. Sibghatullah AU - Naz, Maria AU - Bukhari, Uzma PY - 2022/07/04 Y2 - 2024/03/29 TI - Proliferative Verrucous Leukoplakia with Dysplastic Changes JF - Journal of Bahria University Medical and Dental College JA - J. Bahria Univ. Med. Dent. Coll. VL - 12 IS - 03 SE - Case Report DO - 10.51985/JBUMDC202238 UR - https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/953 SP - 172-174 AB - <p><span class="fontstyle0">Proliferative verrucous leukoplakia is one of the rare premalignant white lesions with highest conversion rate to malignancy.<br>It grows gradually and irreversibly with multifocal presentation, exophytic and verrucous appearance. This lesion has been<br>reported resistant to all therapeutic approaches including both non-surgical and surgical. Predisposing factors include<br>female gender in the 6</span><span class="fontstyle0">th </span><span class="fontstyle0">decade of life. Proliferative verrucous leukoplakia has the highest tendency to neoplastic transformation<br>and progression to oral squamous cell carcinoma and oral verrucous carcinoma in majority of the cases. The case of<br>proliferative verrucous lesion clinically appearing benign presented here but on histopathology proven dysplasia in a patient<br>with the history of smoking which he stopped six years back.</span> </p> ER -