TY - JOUR AU - Shams, Nadia AU - Baloch, Muhammad Hussain AU - Niaz, Furquana AU - Meraj, Lubna AU - Ali, Mubarak PY - 2022/07/04 Y2 - 2024/03/28 TI - Echocardiography Based Assessment of Cardiac Function in Patients With Renocardiac Syndrome JF - Journal of Bahria University Medical and Dental College JA - J. Bahria Univ. Med. Dent. Coll. VL - 12 IS - 03 SE - Original Articles DO - 10.51985/JBUMDC202243 UR - https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/947 SP - 143-147 AB - <p><span class="fontstyle0">Objectives: </span><span class="fontstyle2">There is rising world-wide burden of chronic kidney disease (CKD) with high Cardio-vascular mortality. This<br>research aims to study echocardiography based cardiac function with respect to CKD stages.<br></span><span class="fontstyle0">Study Design and Setting: </span><span class="fontstyle2">This cross-sectional study was conducted at RIHS Islamabad (Jan 2021–Jan 2022) after ethical<br>approval.<br></span><span class="fontstyle0">Methodology: </span><span class="fontstyle2">Total 130 adult CKD cases were included by consecutive sampling. Acute kidney injury and diagnosed/treated<br>cases of cardiac disease were excluded. BMI and GFR was calculated. CKD staging done by KDOQI-classification. Cardiac<br>impairment categorized by ECG and Echocardiography. Data analyzed by SPSS V-22 with Chi-square test.<br></span><span class="fontstyle0">Results</span><span class="fontstyle2">: Amongst 130 CKD cases, there were 66(51%) males and 64(49%) females. Mean age was 60+13.27 years, mean<br>BMI was 24+4.2. Diabetes mellitus was observed in 100(76.9%), hypertension in 122(93.8%). Mean creatinine was<br>4.83mg/dl and mean GFR was 17.84 mL/min/1.73m</span><span class="fontstyle2">2</span><span class="fontstyle2">. Twenty-five(19.2%) patients were on hemodialysis. Mean cardiac<br>EF was 49.18%</span><span class="fontstyle0">. </span><span class="fontstyle2">EF was normal in 39(30%), mildly reduced in 40(30.8%), moderately reduced in 29(22.3%) and severely<br>reduced in 22(16.9%), diastolic dysfunction seen in 08(6.2%). Twenty-five(18.5%) cases had congestive cardiac failure;<br>14(56%) compensated and 11(44%) decompensated CCF. There was significant association between GFR and EF (p&lt;0.0001).<br></span><span class="fontstyle0">Conclusions: </span><span class="fontstyle2">Decline in cardiac function is associated with advanced CKD stages. Cardiac evaluation suggested at initial<br>presentation of CKD, hence diagnosing asymptomatic compensated heart failure. Study finds high burden of diabetes,<br>hypertension, anemia and IHD in CKD cases. GFR should be used rather than isolated creatinine in CKD. High clinical<br>suspicion and early intervention may lead to better outcome</span> </p> ER -