Chikungunya Fever

Authors

  • Hina Wasti
  • Shomaila Farman
  • Uzma Naseeb

Keywords:

Aedes mosquito, Chikungunya fever, IgM antibody, Severe sepsis, Vector-borne infections

Abstract

Chikungunya fever is caused by the chikungunya virus (CHIKV), a mosquito-borne emerging pathogen, which was first
revealed on the borders of Mozambique and Tanzania in 1952. Currently it is stretched over 40 countries globally. It is an
arthropod-born virus endemic in Africa, Southeast Asia and India. Aedes aegypti and Aedes albopictus are the mosquito vectors
which spread this virus. Blood, saliva and urine are the samples for investigation. Since there is no definite treatment available,
identifying ways to abolish mosquito populations is the most useful strategy to control the disease. As the virus has facility
for global spread, there is need to take preventive measures as well as rapid diagnostic tests to improve identification of
Chikungunya patients.

References

Taubitz W, Cramer JP, Kapaun A, Pfeffer M, Drosten C, Dobler G, et al. Chikungunya Fever in Travelers: Clinical Presentation and Course. Clin Infect Dis. 2007; 45(1)

Sanyaolu A, Okorie C, Badaru O, Wynveen E, White S, Wallace W, et al. Chikungunya Epidemiology: A Global Perspective. SM J Public Health Epidemiol 2016; 2(2): 1028

Weaver SC. Arrival of Chikungunya Virus in the New World: Prospects for Spread and Impact on Public Health PLoS Neg Tropl Dis. 2014; 8(6): 2921

Thiboutot MM, Kannan S, Kawalekar OU, Shedlock DJ, Khan AS, Sarangan G, et al. Chikungunya: A Pote- ntially Emerging Epidemic? PLoS Neg Tropl Dis. 2010; 4(4):623

Bloch D, Roth NM, Caraballo EV, Muñoz-Jordan J, Hunsperger E, Rivera A, et al. Use of Household Cluster Investigations to Identify Factors Associated with Chikungunya Virus Infection and Frequency of Case Reporting in Puerto Rico. PLOS Negl Trop Dis. 2016; 10(10):1371

Mohan A, Kiran DH, Manohar IC, Kumar DP. Epidemiology, clinical manifestations, and diagnosis of Chikungunya fever: lessons learned from the re-emerging epidemic. Indian J Dermatol. 2010; 55:54-63

Sepúlved DJ, Vera LO, Jara L, Murillo KT, Gonzalez RS, Trampe AL, et al. SAT0495 Chikungunya Viral Arthritis in Mexico: Inflammatory Biomarkers, Disability and Disease Activity Index May Be Predictors of Chronic Arthritis. Ann of the Rheum Dis. 2016; 75(2); 1136

Tsuboi M, Kutsuna S, Kato Y, Nakayama E, Shibasaki K-I, Tajima S, et al. Autochthonous Chikungunya Fever in Traveler Returning to Japan from Cuba. Emerg Infect Dis. 2016; 22(9):1683–5

Andrade DC, Jean S, Clavelou P, Dallel R, Bouhassira D. Chronic pain associated with the Chikungunya Fever: long lasting burden of an acute illness. BMC Infect Dis. 2010; 10: 31

Musso D, Teissier A, Rouault E, Teururai S, Pina J- JD, Nhan T-X. Detection of chikungunya virus in saliva and urine. J Virol. 2016; 13(1): 102

Hassan R, Rahman MM, Moniruzzaman M, Rahim A, Barua S, Biswas R, et al. Chikungunya an emerging infection in Bangladesh: a case series. J of Med Case Rep. 2014; 8(1): 67

Ramsauer K, Schwameis M, Firbas C, Müllner M, Putnak RJ, Thomas SJ, et al. Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomized, double-blind, placebo-controlled, active-comparator, first-in-man trial. The Lanc Infect Dis. 2015; 15(5):519–27

Diallo M, Dia I, Diallo D, Diagne CT, Ba Y, Yactayo S. Perspectives and Challenges in Entomological Risk Assessment and Vector Control of Chikungunya. The Jour of Infect Dis. 2016; 214: 459-65

Lum F-M, Teo T-H, Lee WWL, Kam Y-W, Renia L, Ng LFP. An Essential Role of Antibodies in the Control of Chikungunya Virus Infection. J Immunol. 2013; 190 (12):6295–302

Andrade DC, Jean S, Clavelou P, Dallel R, Bouhassira D. Chronic pain associated with the Chikungunya Fever: long lasting burden of an acute illness. BMC Infect Dis. 2010; 10:31

Downloads

Published

2017-06-05

How to Cite

Wasti, H. ., Farman, S. ., & Naseeb, U. . (2017). Chikungunya Fever. Journal of Bahria University Medical and Dental College, 7(2), 125–127. Retrieved from https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/249