New Aspects of 2-Adrenergic Agonists

Authors

  • Touseef Sayyar

Keywords:

Beta2-adrenergic receptors, Beta 2-adrenergic receptor agonists, Indications, New aspects

Abstract

Beta2-adrenergic receptor agonists is a class of medications that act on the 2-adrenergic receptors. They are mostly used to treat asthma and other respiratory problems at present. However, the newer research have highlighted that they can be utilized in numerous other disorders like Congenital Myasthenic Syndrome, Down syndrome, Amyotrophic lateral sclerosis, Idiopathic Stuttering Priapism & Dyslipidemia etc.

References

Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen

SG, Thian FS, KobilkaTS .High-resolution crystal stru-

cture of an engineered human 2-adrenergic G protein-

coupled receptor.Science 2007; 318 ( 3): 1266-73

Birrel MA, Bonvini SJ, Michael A , James B.The role

of adenylyl cyclase isoform 6 in ß-adrenoceptor signalling

in murine airways. BJP.2014;173(2): 253-412

Pagon RA, Adam MP, Ardinger HH, Wallace SE, Ame-

miya A, Bean LJH et al .Congenital Myasthenic Synd-

romes. AJHG .2012; 91( 1) :193-201

Burke G, Hiscock A, Klein A, NiksEH. Salbutamol ben-

efits children with congenital myasthenic syndrome due

to DOK7 mutations in Neuromuscular Disorders . Else-

vier 2013 ;23( 2): 170-5

Dang v, Medina B, Das D, Moghadam S, Martin KJ.F-

ormoterol Improves Cognitive Function and Promotes

Dendritic Complexity in a Mouse Model of Down Syn-

drome Biological Psychiatry .Elsevier.2014 ;75( 3):179-

Jesinkey SR, Funk JA, Stallons LJ, Wills LP .Formoter-

olrestores mitochondrial and renal function after isch-

emia-reperfusion injury.JASN. 2013;21(3):160-76

Cozzolinoa M, CarrìaMT. Mitochondrial dysfunction

in ALS Progress in Neurobiology.Elsevier .2012; 97 (2):

-66

Bartus RT, Bétourné A, Basile A, Peterson BL. 2-Adre-

noceptor agonists as novel, safe and potentially effective

therapies for Amyotrophic lateral sclerosis (ALS) in

Neurobiology of Disease.Elsevier;2015; 85 (1):11–24

Migliorini F, Porcaro AB, BaldassarreR ,ArtibaniW.

Idiopathic stuttering priapism treated with salbutamol

orally.Androgolia. 2015;1439(1):13-22

Maki KC, Skorodin MS, Jessen JH, Laghi F. Effects of

oral albuterol on serum lipids and carbohydrate metabo-

lism in healthy men .Elsevier.1996; 45( 6) :712-7

Yanrui Ye, Hang Xu, Quan L, Zhu L, Zeng J, Zhou T,

et al. The Lipid-lowering Effects of R-bambuterol in

Healthy Chinese Volunteers .Elsevier .2015; 2( 4):356-

Zhou HC, Sun YY, Cai W, He XT, Yi F, Li BM.Activat-

ion of 2-adrenoceptor enhances synaptic potentiation

and behavioral memory via cAMP-PKA signaling in

the medial prefrontal cortex of rats Cold Spring Harbor

Laboratory Press.2013; 3(2):54-65

Davidson MH. ß2-Agonism: A potential therapeutic

target for dyslipidemia.Elsevier.2015; 2(4):356-64

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Published

2015-12-03

How to Cite

Sayyar, T. . (2015). New Aspects of 2-Adrenergic Agonists. Journal of Bahria University Medical and Dental College, 5(4), 201–202. Retrieved from https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/144