Frequency of Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Complications
DOI:
https://doi.org/10.51985/JBUMDC2022111Keywords:
Endoscopic Retrograde Cholangiopancreatography, Pancreatitis, EndoscopyAbstract
Objective: Endoscopic Retrograde Cholangiopancreatography (ERCP) is a highly technical procedure that carries some
risks associated with it. It consolidates the utilization of an endoscope with X-ray to look at the biliary and pancreatic
channels with the ability to intervene when indicated to address problems identified during surgery. This study aimed to
determine the frequency
Study Design & Setting: Cross-sectional study design at Dow Hospital Karachi.
Methodology: The patients with the age ranging from 18 to 60 years who had endoscopies were taken from July 2020 to
February 2021. All the pregnant patients and those who were unwilling to participate in the study were excluded from the
study. The data were collected from the patients and they were kept under observation for 4 – 6 hours after ERCP to monitor
the development of an immediate complication. The findings were recorded only at 48 hours of the procedure.
Results: The age of the participants was 37±12 years on average. The complications were recorded with pancreatitis at
36% followed by 34.5% bleeding and 29% perforation. 92% of the procedures were successful.
Conclusions: In conclusion, while ERCP is generally considered a safe and effective procedure, it is not without risks.
The most common complications of ERCP are pancreatitis, bleeding, and perforation
References
Bor R, Madácsy L, Fábián A, Szepes A, Szepes ZJWJoGE.
Endoscopic retrograde pancreatography: When should we do
it? 2015;7(11):1023. doi: 10.4253/wjge.v7.i11.1023
Cohen LB, DeLegge MH, Aisenberg J, Brill JV, Inadomi JM,
Kochman ML, et al. AGA Institute review of endoscopic
sedation. 2007;133(2):675-701. DOI:https://doi .org/10. 1053
/j.gastro.2007.06.002
Weaver J. The Latest ASA Mandate: CO2 Monitoring For
Moderate and Deep Sedation. Anesthesia Progress.
;58(3):111-2. doi.org/10.2344/0003-3006-58.3.111
Kim YS, Kim M-H, Jeong SU, Lee BU, Lee SS, Park DH,
et al. Comparison between Midazolam Used Alone and in
Combination with Propofol for Sedation during Endoscopic
Retrograde Cholangiopancreatography. ce. 2014;47(1):94-
DOI: https://doi.org/10.5946/ce.2014.47.1.94
Katsinelos P, Lazaraki G, Chatzimavroudis G, Gkagkalis S,
Vasiliadis I, Papaeuthimiou A, et al. Risk factors for therapeutic
ERCP-related complications: an analysis of 2,715 cases
performed by a single endoscopist. Ann Gastroenterol.
;27(1):65-72. PMID: 24714755
Goudra BG, Singh PM, Sinha ACJSJoA. Outpatient endoscopic
retrograde cholangiopancreatography: Safety and efficacy of
anesthetic management with a natural airway in 653
consecutive procedures. 2013;7(3):259. DOI: 10.4103/1658-
X.115334
Castañera EP, López PR, Delgado AÁ, Núñez FM, Martínez
FG, Guardado AVJRededoodlSEdPD. Predictive factors for
post-ERCP bleeding. Influence of direct oral anticoagulants.
;113(8):591-6. DOI: 10.17235/reed.2020.7547/2020
Singh VK. Managing Perforations Related to Endoscopic
Retrograde Cholangiopancreatography. Gastroenterol Hepatol
(N Y). 2016;12(4):260-2. PMID: 27231459
Freeman ML, Nelson DB, Sherman S, Haber GB, Herman
ME, Dorsher PJ, et al. Complications of Endoscopic Biliary
Sphincterotomy. 1996;335(13):909-19. DOI: 10.1056
/NEJM199609263351301
Davis J, Sreevastava DK, Dwivedi D, Gadgi S, Sud S, Dudeja
P. A Comparison of Stress Response between Insertion of
Gastro-laryngeal Tube and Endotracheal Intubation in Patients
Undergoing Upper Gastrointestinal Endoscopic Procedures
for Endoscopic Retrograde Cholangiopancreatography. Anesth
Essays Res. 2019;13(1):13-8. doi: 10.4103/aer.AER_9_19
Wang J, Shen Y, Zhong Z, Wu S, Zheng L. Risk Factors for
Post-Endoscopic Retrograde Cholangiopancreatography
(ERCP) Pancreatitis and the Effect of Octreotide Combined
with Nonsteroidal Anti-Inflammatory Drugs on Preventing
Its Occurrence. Med Sci Monit. 2018;24:8964-9. doi:
12659/MSM.911914
Bae SS, Lee DW, Han J, Kim HG. Risk factor of bleeding
after endoscopic sphincterotomy in average risk patients.
Surgical Endoscopy. 2019;33(10):3334-40. doi.org/10.1007
/s00464-018-06623-8
Langerth A, Isaksson B, Karlson B-M, Urdzik J, Linder S.
ERCP-related perforations: a population-based study of
incidence, mortality, and risk factors. Surgical Endoscopy.
;34(5):1939-47. doi.org/10.1007/s00464-019-06966-w
Zhong H, Wang X, Yang L, Miao L, Ji G, Fan ZJM. Modified
transprepancreatic septotomy reduces postoperative
complications after intractable biliary access. 2018;97(1). doi:
1097/MD.0000000000009522
Ergin E, Oruç N, Ersöz G, Tekeºin O, Özütemiz Ö. Prognosis
and risk factors of ERCP pancreatitis in elderly. Scientific
Reports. 2021;11(1):15930. doi.org/10.1038/s41598-021-
-8
Loperfido S, Angelini G, Benedetti G, Chilovi F, Costan F,
De Berardinis F, et al. Major early complications from
diagnostic and therapeutic ERCP: a prospective multicenter
study. 1998;48(1):1-10. doi.org/10.1016/S0016-5107
(98)70121-X
Masci E, Toti G, Mariani A, Curioni S, Lomazzi A, Dinelli
M, et al. Complications of diagnostic and therapeutic ERCP:
a prospective multicenter study. 2001;96(2):417-23.
doi.org/10.1016/S0002-9270(00)02387-X
Rabenstein T, Schneider H, Bulling D, Nicklas M, Katalinic
A, Hahn E, et al. Analysis of the risk factors associated with
endoscopic sphincterotomy techniques: preliminary results
of a prospective study, with emphasis on the reduced risk of
acute pancreatitis with low-dose anticoagulation treatment.
;32(01):10-9. DOI: 10.1055/s-2000-138
Cotton PBJGe. Outcomes of endoscopy procedures: struggling
towards definitions. 1994;40(4):514-8. doi.org/10.1016/S0016-
(94)70228-4
Bauerle K, Greim CA, Schroth M, Geisselbrecht M, Köbler
A, Roewer NJBjoa. Prediction of depth of sedation and
anaesthesia by the NarcotrendTM EEG monitor.
;92(6):841-5. doi.org/10.1093/bja/aeh142
Cheon YK, Cho KB, Watkins JL, McHenry L, Fogel EL,
Sherman S, et al. Frequency and severity of post-ERCP
pancreatitis correlated with extent of pancreatic ductal
opacification. 2007;65(3):385-93. doi.org/10.1016/ j.gie
.2006.10.021
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Asma Abdul Razzak, Muhammad Raza
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Journal of Bahria University Medical & Dental College is an open access journal and is licensed under CC BY-NC 4.0. which permits unrestricted non commercial use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc/4.0