Heterotopic Pregnancy Following Ovulation Induction By Clomiphene Citrate And A Normally Growing Intrauterine Pregnancy: A Case Report

Authors

  • Khalida Nasreen
  • Samreen Iqbal
  • Atiya Fasih

Keywords:

Heterotopic pregnancy, Ovulation induction, Clomiphene citrate, Laparotomy

Abstract

ABSTRACT: A heterotopic pregnancy is defined as the presence of a combined intrauterine and ectopic pregnancy. Heterotopic pregnancy is rare, estimated to occur in 1/30,000 pregnancies. It is also reported to be as high as 1% after the use of assisted reproductive technology. Simultaneous extra and intrauterine pregnancy after the induction of ovulation with clomiphene citrate has been reported. Clomiphene citrate which increases the rate of twining could be associated with a heterotopic pregnancy rate of 1/900, which is much less than using assisted reproductive technology. Heterotopic pregnancies are diagnostic and therapeutic challenges for obstetricians. If they continue without diagnosis, a life- threatening situation may occur even when surgical intervention with laparotomy is performed. 

References

Avitabile NC, Kaban NL, Siadecki SD, Lewiss RE, Saul T. Two Cases of Heterotopic Pregnancy Review of the Literature and Sonographic Diagnosis in the Emergency Department. ©2015 by the American Institute of Ultrasound in Medicine J Ultrasound Med 2015; 34:527–30.

Umranikar S, Umranikar A, Rafi J, Bawden P, Umranikar S, O'Sullivan B, Moors A. Acute presentation of a heterotopic pregnancy following spontaneous conception: a case report. Cases J. 2009; 2: 936-9.

Ghulmiyyah LM, Eid J, Nassar AH, Mirza FG, Nassif J. Recurrent twin pregnancy, with the second heterotopic pregnancy, following clomiphene citrate stimulation: an unusual case and a review of the literature. Surg Technol Int. 2014; 25:195-200.

Chen KH, Chen LR. Rupturing heterotopic pregnancy mimicking acute appendicitis. 2014; 53 (3): 401–3.

Ljuca D. Heterotopic pregnancy in natural conception – our initial experience: case report. Acta Clin Croat 2011; 50:249-52

Fukuda T, Inoue H, Toyama Y, Ichida T, Uzawa Y, Monma M, et al. Bilateral tubal and intrauterine pregnancies diagnosed at laparoscopy., J Obstet Gynaecol Res. 2014; 40(10):2114-7. doi: 10.1111/jog.12458. Epub 2014 Sep 17

Naki MM, Tekcan C, Uysal A , Güzin K, Yücel N. Archives of Gynecology and Obstetrics2006; 274 (3): 181-8

Honarbakhsh A, Khoori E , Mousavi S. Case report Heterotopic pregnancy following ovulation induction by Clomiphene and a healthy live birth: a case report. Journal of Medical Case Reports 2008, 2:390.

Fouedjio JH, Fouelifack FY, Fouogue JT, Sando Z. Ruptured heterotopic pregnancy in a natural conception cycle: a case report at the Yaounde central Hospital (Cameroon). Pan Afr Med J. 2013; 16: 106.

Ikechukwu E, Adeleni M. Heterotopic pregnancy with live infant. Ann 2013 Jan-Mar; 12 (1):43-5. doi: 10.4103/1596-3519.108251.

Oral S, Akpak YK, Nilay Karaca N, Babacan A, Savan K. Case Report Cornual Heterotopic Pregnancy after Bilateral Salpingectomy and Uterine Septum Resection Resulting in Term Delivery of a Healthy Infant. Case Reports in Obstetrics and Gynecology. Volume 2014 (2014), Article ID 157030, 3 pages.

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Published

2015-03-03

How to Cite

Nasreen, K. ., Iqbal, . S. ., & Fasih, . A. . (2015). Heterotopic Pregnancy Following Ovulation Induction By Clomiphene Citrate And A Normally Growing Intrauterine Pregnancy: A Case Report. Journal of Bahria University Medical and Dental College, 5(1), 43–44. Retrieved from https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/103

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Section

Case Report