Dilemma of Dantrolene: A life-saving drug unavailable in Pakistan
DOI:
https://doi.org/10.51985/JBUMDC2022137Abstract
Malignant hyperthermia (MH) is brought on by a number
of anaesthetic drugs, primarily succinylcholine and inhalation
anesthetics.1 It is a hypermetabolic reaction in those who
are genetically predisposed
References
Blais A. Succinylcholine, malignant hyperthermia and
rhabdomyolysis. CMAJ. 2022;194(25):E878. DOI: https://doi.
org/10.1503/cmaj.146480-l
Neto CN, Neville MF, da Silva HC. Anesthesia for malignant
hyperthermia susceptible patients. InTreatments, Mechanisms,
and Adverse Reactions of Anesthetics and Analgesics 2022
(pp. 3-14). Academic Press. https://doi.org/10.1016/B978-0-
-820237-1.00001-6
Dar IS, Ashraf M. Pathophysiology of malignant hyperthermia.
Perioperative Anaesthetic Emergencies. 2021:272.
Bin X, Wang B, Tang Z. Malignant Hyperthermia: A Killer
If Ignored. Journal of PeriAnesthesia Nursing. 2022 Apr 10.
https://doi.org/10.1016/j.jopan.2021.08.018
Hopkins PM, Girard T, Dalay S, Jenkins B, Thacker A, Patteril
M, McGrady E. Malignant hyperthermia 2020: Guideline
from the Association of Anaesthetists. Anaesthesia. 2021;
(5):655-64. https://doi.org/10.1111/anae.15317
Smith A. Donating Dantrolene: Development and
Implementation of a Malignant Hyperthermia Program in a
Scarce Resource Setting. AANA journal. 2022;90(4)
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Tahir Ali, Habib Feroz Kapadia
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Journal of Bahria University Medical & Dental College is an open access journal and is licensed under CC BY-NC 4.0. which permits unrestricted non commercial use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc/4.0